MétaCan
Menu
← Back to cohort
Record W4414556923 · doi:10.1038/s41598-025-18467-z

Size distribution and viral RNA load of influenza virus-laden airborne particles emitted from pigs over the course of an H1N1 infection

2025· article· en· W4414556923 on OpenAlexaff
Lan Wang, José Morán, My Yang, Bernard A. Olson, Christopher J. Hogan, Montserrat Torremorell

Bibliographic record

VenueScientific Reports · 2025
Typearticle
Languageen
FieldMedicine
TopicInfluenza Virus Research Studies
Canadian institutionsUniversity of Ottawa
FundersNational Institute of Food and Agriculture
KeywordsTransmission (telecommunications)Airborne transmissionViral sheddingViral loadInfluenza A virusVirusInoculation

Abstract

fetched live from OpenAlex

Airborne influenza infections cause significant disease in animals and people. However, there is limited information on the dynamics of viral emissions and size distribution of airborne virus-laden particles generated by infected animals. In this study, we used pigs as a model for the airborne transmission of influenza A virus (IAV) and we quantified nasal shedding, viral RNA load of airborne particles emitted from pigs experimentally infected with a swine-origin H1N1 IAV, and characterized the size distribution of the virus-laden particles generated from infected pigs over the course of infection. We found that the peak of nasal shedding and airborne IAV-laden particles across multiple size ranges took place at 2 days post inoculation (DPI), with higher viral RNA load found in larger particles. The amount of airborne IAV emitted by infected pigs over the course of infection in particles > 8 μm was significantly higher than that in particles between 0.22 and 1.7 μm. These findings help understand the risk of airborne transmission of IAV in pigs and provide information to help control airborne infections more effectively.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.001
Threshold uncertainty score0.002

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.027
GPT teacher head0.352
Teacher spread0.325 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

Explore more

Same venueScientific Reports→Same topicInfluenza Virus Research Studies→French-language works237,207→