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Record W4414598841 · doi:10.1101/2025.09.09.25333678

Computed Tomography Orodental Sub-volume Imaging Annotation Dataset of Head and Neck Cancer Radiation Therapy Patients

2025· preprint· en· W4414598841 on OpenAlexaff
Zaphanlene Kaffey, Austin H. Castelo, Renjie He, Lisanne V. van Dijk, Dong Joo Rhee, Congjun Wang, He Wang, Kareem A. Wahid, Sonali Joshi, Parshan Gerafian, Natalie West, Sarah Mirbahaeddin, Jaqueline Curiel, Amal Shekha, Praise Oderinde, Alaa Mohamed Shawky Ali, Andrew Hope, Erin Watson, Ruth Aponte Wesson, Steven J. Frank, Carly E. A. Barbon, Kristy K. Brock, Mark S. Chambers, Muhammad F. Walji, Katherine A. Hutcheson, Stephen Y. Lai, Clifton D. Fuller, Mohamed A. Naser, Amy C. Moreno, Laia Humbert‐Vidan

Bibliographic record

VenuemedRxiv · 2025
Typepreprint
Languageen
FieldMedicine
TopicHead and Neck Cancer Studies
Canadian institutionsPrincess Margaret Cancer Centre
FundersCenter for Clinical and Translational Sciences, University of Texas Health Science Center at HoustonNational Cancer InstituteNational Institutes of HealthNederlandse Organisatie voor Wetenschappelijk OnderzoekNational Institute of Dental and Craniofacial ResearchUniversity of Texas MD Anderson Cancer CenterCancer Prevention and Research Institute of TexasZonMwUniversity of Texas Health Science Center at HoustonNational Aeronautics and Space Administration
KeywordsOsteoradionecrosisHead and neck cancerComputed tomographyRadiation therapySegmentationRadiation treatment planningProtocol (science)Image-guided radiation therapy

Abstract

fetched live from OpenAlex

Abstract Accurate delineation of orodental structures on computed tomography (CT) is critical for image-guided assessments of radiation-associated bone injury. This dataset comprises curated CT imaging and expert-defined segmentation masks for 60 patients with head and neck cancer treated with radiotherapy (RT), including delineations of mandibular and maxillary sub-volumes and individual teeth. Segmentation guidelines were informed by anatomical differences across sub-regions and aligned with the ClinRad osteoradionecrosis (ORN) staging system. The dataset includes converted NIfTI files of simulation CT images, RT dose distributions, and delineated structures. All segmentations were performed manually using a standardized protocol in a commercial treatment planning system and converted to research-ready formats using open-source tools. This dataset may facilitate the development and validation of automated segmentation tools, dose mapping applications, and image-based ORN detection pipelines in head and neck cancer survivors.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.002
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Dataset · Consensus signal: Dataset
Teacher disagreement score0.012
Threshold uncertainty score0.024

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.002
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0010.000
Open science0.0010.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0070.006

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.019
GPT teacher head0.312
Teacher spread0.293 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreDataset

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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Same venuemedRxiv→Same topicHead and Neck Cancer Studies→French-language works237,207→