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Record W4414646545 · doi:10.1038/s42003-025-08792-4

Temporal dedifferentiation of neural states with age during naturalistic viewing

2025· article· en· W4414646545 on OpenAlexafffund
Selma Lugtmeijer, Djamari Oetringer, Linda Geerligs, Karen L. Campbell

Bibliographic record

VenueCommunications Biology · 2025
Typearticle
Languageen
FieldNeuroscience
TopicFunctional Brain Connectivity Studies
Canadian institutionsBrock University
FundersBiotechnology and Biological Sciences Research CouncilNatural Sciences and Engineering Research Council of CanadaMedical Research CouncilDirectorate for Biological SciencesCanadian Institutes of Health ResearchCanadian Network for Research and Innovation in Machining Technology, Natural Sciences and Engineering Research Council of CanadaNederlandse Organisatie voor Wetenschappelijk OnderzoekCanada Research ChairsGovernment of Canada
KeywordsFunctional magnetic resonance imagingNeural activitySegmentationNeural correlates of consciousnessEvent (particle physics)Artificial neural networkTime perception

Abstract

fetched live from OpenAlex

While life is experienced continuously, we perceive it as a series of events. At a neural level, this event segmentation process has been linked to changes in neural states. An open question is whether neural states differ with age. Participants (N = 577) from the CamCAN cohort viewed an 8-min movie during functional magnetic resonance imaging. A data-driven state segmentation method was used to identify neural state changes. To study the effects of age, participants were sorted into 34 age groups. We show that neural states become significantly longer with increasing age, particularly in visual and ventromedial prefrontal cortices. Event boundaries overlapped with state changes in superior temporal and dorsomedial prefrontal regions, but there was no effect of age on this relationship. Our results suggest reduced temporal differentiation of successive neural states with increasing age. Nevertheless, preserved alignment between neural states and perceived events suggests coarse event segmentation remains intact.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.002
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.002
Threshold uncertainty score0.005

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.002
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.058
GPT teacher head0.323
Teacher spread0.265 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations2
Published2025
Admission routes2
Has abstractyes

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