THE USE OF CLOZAPINE IN PAKISTAN: A STUDY BASED ON CLOZARIL PATIENTS MONITORING SYSTEM (CPMS)
Bibliographic record
Abstract
Clozapine is the drug of first choice for Treatment Resistant Schizophrenia (TRS) but it is underutilized and very little information is available about its use in developing countries. We analyzed the medical record of patients who are currently on the data base of Clozapine Monitoring System in Pakistan. Only 1256 patients, almost all concentrated in four major cities were receiving the Clozapine. The mean maintenance dose of Clozapine was 230mg and only a quarter of the psychiatrists working in Pakistan were prescribing Clozpine. The reasons for inadequate use of Clozapine need to be investigated and psychiatric training and perception of the drug needs to be improved in view of the estimated high prevalence of TRS in developing countries.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.003 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.000 | 0.002 |
| Science and technology studies | 0.001 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.001 | 0.000 |
| Research integrity | 0.000 | 0.002 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".