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Record W4414661709 · doi:10.1093/evlett/qrag016

Competition constrains parasite adaptation to thermal heterogeneity

2025· article· en· W4414661709 on OpenAlexafffund
Samuel T. E. Greenrod, Daniel Cazares, Weronika A Slesak, Tobias E. Hector, R. Craig MacLean, Kayla C. King

Bibliographic record

VenueEvolution Letters · 2025
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicEvolution and Genetic Dynamics
Canadian institutionsUniversity of British Columbia
FundersNatural Environment Research CouncilNatural Sciences and Engineering Research Council of CanadaUK Research and Innovation
KeywordsCompetition (biology)Adaptation (eye)Generalist and specialist speciesSelection (genetic algorithm)Experimental evolutionLytic cycleRange (aeronautics)Local adaptationIntraspecific competition

Abstract

fetched live from OpenAlex

Abstract Temporal thermal heterogeneity is expected to favour intermediate, generalist phenotypes that can maintain growth across a broad thermal range but have sub-optimal growth at any single temperature. Yet, thermal variation typically occurs in the presence of additional selection pressures which may interact to constrain adaptation to temperature. We propagated competing lytic viral parasites (bacteriophages, thermal specialist φ14–1 and thermal generalist φLUZ19) of Pseudomonas aeruginosa under fluctuating temperatures (37°C–42°C) in monoculture and in co-culture. Without competition, fluctuating temperatures resulted in intermediate thermal phenotypes in the phage φ14–1 and, in both phages, resulted in more variable evolutionary outcomes compared to static conditions. Selection from both fluctuating temperatures and competition accelerated thermal adaptation in the phage φ14–1. However, co-selection led to restricted thermal adaptation, lower genetic distance from ancestor, and fewer putative adaptive mutations in the phage φLUZ19. Our study highlights the potential for variable adaptive capacity in interacting communities amidst global climate change.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.002
Threshold uncertainty score0.007

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0010.000
Open science0.0000.001
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.007
GPT teacher head0.251
Teacher spread0.244 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes2
Has abstractyes

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