Changes in Naturalistic Viewing in Healthy Aging and Amnestic Mild Cognitive Impairment
Bibliographic record
Abstract
Visual exploration-where the eyes move and when-is guided by prior experiences. Memory-guided viewing behavior is altered in healthy aging and is further disrupted in amnestic mild cognitive impairment (aMCI), a condition in which there is accelerated structural and functional decline of the hippocampus and associated medial temporal lobe structures (HC/MTL). Computational modeling has demonstrated the potential for rapid information flow from the HC/MTL to regions responsible for the cognitive control of eye movements, such that visual exploration behavior could be impacted in the moment and on an ongoing fashion. It was predicted here, then, that older adults and individuals with aMCI would show changes in naturalistic viewing compared to younger adults, even in the absence of any memory task. Multivariate analyses revealed that viewing for younger adults was characterized by larger saccade amplitudes and a larger area of exploration; the opposite pattern was reliably expressed by individuals with aMCI. Viewing patterns of healthy older adults were associated with shorter gaze durations. The entropy of viewing in older adults was associated with overall cognitive status, as determined by the Montreal Cognitive Assessment, highlighting the top-down influence of cognitive function on active vision. Lower scores on the memory subtest were reliably associated with a pattern of viewing characterized by fewer fixations (with longer durations), saccades, regions explored, smaller area of exploration, and lower entropy, mimicking some of the viewing features of the aMCI group and suggesting that increasing HC/MTL decline results in less exploratory viewing patterns. These findings reveal the ongoing influence of the hippocampus and its extended system on moment-to-moment naturalistic viewing.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".