Low‐Dose Computed Tomography Image Denoising Vision Transformer Model Optimization Using Space State Method
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Bibliographic record
Abstract
ABSTRACT Low‐dose computed tomography (LDCT) is widely used to promote reduction of patient radiation exposure, but the associated increase in image noise poses challenges for diagnostic accuracy. In this study, we propose a Vision Transformer (ViT)‐based denoising framework enhanced with a State Space Optimizing Block (SSOB) to improve both image quality and computational efficiency. The SSOB upgrades the multihead self‐attention mechanism by reducing spatial redundancy and optimizing contextual feature fusion, thereby strengthening the transformer's ability to capture long‐range dependencies and preserve fine anatomical structures under severe noise. Extensive evaluations on randomized and categorized datasets demonstrate that the proposed model consistently outperforms existing state‐of‐the‐art denoising approaches. It achieved the highest average SSIM (up to 6.10% improvement), PSNR values (36.51 ± 0.37 dB on randomized and 36.30 ± 0.36 dB on categorized datasets), and the lowest RMSE, surpassing recent CNN‐transformer‐based denoising hybrid models by approximately 12%. Intensity profile analysis further confirmed its effectiveness, showing sharper edge transitions and more accurate gray‐level distributions across anatomical boundaries, closely aligning with ground truth and retaining subtle diagnostic features often lost in competing models. In addition to improved reconstruction quality, the SSOB‐empowered ViT achieved notable computational gains. It delivered the fastest inference (0.42 s per image), highest throughput (2.38 images/s), lowest GPU memory usage (750 MB), and smallest model size (7.6 MB), alongside one of the shortest training times (6.5 h). Compared to legacy architectures, which required up to 16 h of training and substantially more resources, the proposed model offers both accuracy and deployability. Collectively, these findings establish the SSOB as a key component for efficient transformer‐based LDCT denoising, addressing memory and convergence challenges while preserving global contextual advantages.
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Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.001 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it