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Record W4414751360 · doi:10.1186/s12885-025-14666-z

Lung cancer stage at diagnosis and immigrant English/French language proficiency: a retrospective population level cohort study of urban residents in Ontario, Canada

2025· article· en· W4414751360 on OpenAlexafffundabout
J. Zhong, Xiaoxuan Han, Aïsha Lofters, Jastaranpreet Singh, Geetanjali D. Datta

Bibliographic record

VenueBMC Cancer · 2025
Typearticle
Languageen
FieldMedicine
TopicGlobal Cancer Incidence and Screening
Canadian institutionsWomen's College HospitalPublic Health OntarioUniversity of Toronto
FundersPeter Gilgan FoundationUniversity of TorontoCanadian Cancer Society
KeywordsSocioeconomic statusSurgical oncologyImmigrationRetrospective cohort studyLung cancerStage (stratigraphy)Cohort studyFluencyPopulation

Abstract

fetched live from OpenAlex

BACKGROUND: Lung and bronchial cancer is the most diagnosed cancer among both sexes in Canada and has one of the lowest survival rates. METHODS: This population level retrospective cohort study examined the associations between the lung cancer stage at diagnosis and English/French fluency. The study used multiple linked health-administrative databases to create a cohort of urban-dwelling Ontarian immigrants and long-term residents aged 45-105 diagnosed with incident lung cancer between 1 January 2010 and 31 December 2020. Modified Poisson regression was used to examine the risk of diagnosis at early vs. late stages among immigrants who do not speak English or French fluently compared with immigrants who speak English or French fluently. The fully adjusted model included age, sex, neighborhood-area income quintile, lung cancer type, number of primary care visits prior to diagnosis, and region of origin. RESULTS: Approximately 57.7% of the 96,613 people diagnosed with incident lung cancer between 2010 and 2020 were diagnosed at the late stage. Non-English/French fluent immigrants were no more likely to be diagnosed at a late stage than English/French fluent immigrants and long-term residents (57.6% vs. 57.8% and 57.7%). However, in fully adjusted models, people living in lower neighborhood income quintiles were more likely to be diagnosed at a late stage (e.g., income quintile 1 [lowest] vs. quintile 5 [highest]: [ARR 1.08; 95% CI: 1.02-1.15]), as were immigrants from the Caribbean [ARR 1.16; 95% CI: 1.05-1.29] and South Asia [ARR 1.10; 95% CI: 1.02-1.19]. CONCLUSIONS: Although lung cancer is frequently diagnosed at a late stage in Ontario and we found socioeconomic inequalities, fluency in Canada's official languages was not associated with late diagnosis in this study.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.007
Threshold uncertainty score0.998

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.033
GPT teacher head0.328
Teacher spread0.295 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes3
Has abstractyes

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