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Record W4414797643 · doi:10.1002/9781394343935.ch15

Status of Regulation on the Per‐ and Polyfluoroalkyl Substances Across the Globe

2025· other· en· W4414797643 on OpenAlexaboutno aff
Manikanta M. Doki, Lakshmi Pathi Thulluru, Akash Tripathi, Shamik Chowdhury, Makarand M. Ghangrekar

Bibliographic record

Venuenot available
Typeother
Languageen
FieldEnvironmental Science
TopicPer- and polyfluoroalkyl substances research
Canadian institutionsnot available
Fundersnot available
KeywordsGlobeEuropean unionSAFERGlobal healthHuman healthDeveloping countryPolitics

Abstract

fetched live from OpenAlex

Per- and polyfluoroalkyl substances (PFAS) have been considered global environmental contaminants due to their persistence, bioaccumulation, and potential adverse health effects. This chapter provides an extensive overview of the regulatory status of PFAS worldwide. It explores country-specific regulations, including the United States, the European Union (EU), the United Kingdom, Canada, Australia, India, Japan, and other developing nations. The chapter also examines the roles of global organizations such as the Stockholm Convention, the United Nations Environment Programme UNEP), the Organisation for Economic Cooperation and Development (OECD), and the International Pollutants Elimination Network (IPEN)in shaping international policies. The discrepancies in regulatory standards and guidelines and the scientific, economic, and political factors influencing these disparities are also analyzed. Further, the key challenges in PFAS regulation, encompassing technological constraints, data deficiencies, and industrial resistance, are also discussed. Finally, the chapter delineates future perspectives on harmonizing global standards, advancing safer alternatives, and strengthening capacity in developing regions. This chapter, therefore, underscores the pressing need for coordinated global efforts to manage PFAS risks effectively and sustainably.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.004
metaresearch head score (Gemma)0.003
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: none
Teacher disagreement score0.023
Threshold uncertainty score0.045

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0040.003
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0020.004
Science and technology studies0.0010.002
Scholarly communication0.0050.003
Open science0.0020.002
Research integrity0.0020.002
Insufficient payload (model declined to judge)0.0110.002

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.017
GPT teacher head0.297
Teacher spread0.280 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations2
Published2025
Admission routes1
Has abstractyes

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Same topicPer- and polyfluoroalkyl substances researchFrench-language works237,207