Biotransformation of perfluorooctanoic acid by a newly isolated Stenotrophomonas acidaminiphila OA1 strain from Quebec
Bibliographic record
Abstract
Perfluorooctanoic acid (PFOA), a persistent and bioaccumulative compound within the broader class of per- and polyfluoroalkyl substances (PFAS), poses a significant challenge to environmental remediation efforts due to its chemical stability and resistance to conventional treatments. This study explores the potential of bacterial strains isolated from a historically petroleum-contaminated site for PFOA biodegradation. Among the three isolates enriched and screened in mineral medium supplemented with 100 mg L⁻¹ PFOA, strain OA1 showed the highest resistance and transformation potential. The selected isolate was identified as Stenotrophomonas acidaminiphila OA1. Batch and fed-batch experiments conducted in enriched medium containing 0.5 mg L⁻¹ PFOA showed no apparent toxicity, with S. acidaminiphila OA1 maintaining stable growth over a 30-day period. PFOA degradation reached 45% under batch conditions, while fed-batch showed lower transformation rates (35%). ¹H NMR spectroscopy suggested the transformation mechanism of PFOA by S. acidaminiphila OA1. This work represents the first report of PFOA biotransformation by Stenotrophomonas acidaminiphila and contributes to the expanding body of knowledge on microbial interactions with perfluorinated compounds. • First report of PFOA biotransformation by Stenotrophomonas acidaminiphila OA1 • No growth inhibition observed in mineral salts medium with 100 mg L⁻¹ PFOA • PFOA removal reached 45% and 32% in batch and fed-batch assays, respectively, over 30 days • ¹H NMR spectrum suggest selective modification of the PFOA backbone
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.001 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.001 |
| Science and technology studies | 0.001 | 0.000 |
| Scholarly communication | 0.001 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.001 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".