MétaCan
Menu
← Back to cohort
Record W4414831251 · doi:10.1093/jas/skaf300.040

326 Genetic evaluation of lamb survival in Canadian sheep using a random regression model.

2025· article· en· W4414831251 on OpenAlexaffabout
Sirlene Fernandes Lázaro, Hinayah Rojas de Oliveira, Flávio S. Schenkel

Bibliographic record

VenueJournal of Animal Science · 2025
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicGenetic and phenotypic traits in livestock
Canadian institutionsUniversity of Guelph
Fundersnot available
KeywordsHeritabilityDomestic sheep reproductionLitterMaternal effectRandom effects modelFlockRegressionAnimal modelAdditive genetic effects

Abstract

fetched live from OpenAlex

Abstract Improving lamb survival is essential for sustainable sheep production, particularly because high prolificacy can lead to increased mortality. The objective of this study was to implement a random regression model to evaluate lamb survival (LS) and estimate genetic parameters across different survival ages, from 1 to 50 days (weaning age). The dataset analyzed included 1,951,084 animals, progeny of 409,304 ewes and 35,118 rams, raised in 2,208 flocks across Canada between 1986 to 2024. A single-trait Bayesian random regression model (RRM), which included the systematic effects of year-month of lambing and age of the dam-class of sex of lambs born, and the random effects of flock-year-management group, litter of birth dam, direct animal additive genetic, animal permanent environment, maternal genetic, and maternal permanent environment. Third-degree Legendre orthogonal polynomials were used to fit the longitudinal direct animal additive genetic, animal permanent environment, maternal genetic random effects and year-month of lambing systematic effect. A homogeneous residual variance across ages was assumed. The average heritability estimates for LS across ages ranged from 0.15 to 0.20 and were consistently higher than when analyzing survival as a categorical trait with five categories (heritability= 0.05), i.e. death at birth: mummified (1) or stillborn (2), between birth and 10 days (3), between 10 and 50 days (4), and survival until weaning at 50 days (5), which is currently the model used to evaluate LS in the Canadian sheep evaluation. Maternal heritability estimates were high across all ages (ranged from 0.52 to 0.53), showing a significant and consistent genetic maternal influence on survival across all ages. This highlights the importance of considering maternal traits in breeding and management strategies to improve lamb survival. The estimated direct genetic correlations across ages ranged from moderate to high (0.75 to 0.90), while the maternal genetic correlations were slightly higher (0.88 to 0.95). These findings suggest that LS between 1 and 50 days of age has a common genetic background indicated by similar heritabilities and moderate to high genetic correlation across ages. Genetic selection based on RRM breeding values is expected to yield greater selection responses for improving lamb survival in Canadian sheep compared to the current evaluation based on a categorical LS trait.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.005
metaresearch head score (Gemma)0.008
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.199
Threshold uncertainty score0.401

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0050.008
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0010.001
Science and technology studies0.0010.000
Scholarly communication0.0010.000
Open science0.0010.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.031
GPT teacher head0.328
Teacher spread0.296 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes2
Has abstractyes

Explore more

Same venueJournal of Animal Science→Same topicGenetic and phenotypic traits in livestock→French-language works237,207→