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Record W4414832496 · doi:10.1016/j.cep.2025.110581

Deep-learning-aided modifier adaptation: synergies with process intensification

2025· article· en· W4414832496 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.
fundA Canadian funder is recorded on the work.

Bibliographic record

VenueChemical Engineering and Processing - Process Intensification · 2025
Typearticle
Languageen
FieldEngineering
TopicSemiconductor materials and devices
Canadian institutionsUniversity of Waterloo
FundersNatural Sciences and Engineering Research Council of Canada
KeywordsConvergence (economics)Adaptation (eye)Process (computing)Artificial neural networkConstraint (computer-aided design)Matching (statistics)

Abstract

fetched live from OpenAlex

Deep learning allows for functions, and their gradients, to be approximated to a high accuracy. Modifier adaptation is a real-time optimization method, which is used to optimize process economics online, and requires gradients to make first-order model corrections. In this work, backpropagated gradients are computed from neural networks trained on historical steady-state data, thus not explicitly requiring any gradient data for training. Data curation and convergence properties are discussed for the proposed method. The deep-learning-aided modifier adaptation is tested in analogous simulated integrated and intensified reactor-separator systems, where it is shown to reconcile plant and model optima in the presence of model mismatch. The case studies show better economics and constraint satisfaction when using the intensified system and the deep-learning-aided modifier adaptation. Further, intensification and deep-learning-aided modifier adaptation are observed to work in tandem as both accelerate the convergence of the plant to its true optima. The proposed method shows how historical data logs can be leveraged to address epistemic uncertainty and improve performance in model-based optimization, especially in intensified systems.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Simulation or modeling · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.409
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.011
GPT teacher head0.226
Teacher spread0.215 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it