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Kinetic Stabilization of [n]Cumulenes by Endgroup Design

2025· article· en· W4414882187 on OpenAlexaff
Bozheng Sun, Matthew A. Johnson, Marc H. Garner, Dominik Wendinger, Yanwen Yang, Lanting Jiang, M.J. Ferguson, Rik R. Tykwinski

Bibliographic record

VenueChemRxiv · 2025
Typearticle
Languageen
FieldChemistry
TopicSynthesis and Properties of Aromatic Compounds
Canadian institutionsUniversity of Alberta
Fundersnot available
KeywordsSteric effectsCarbyneArylMoleculeAbsorption (acoustics)AlkylKinetic energyCumuleneFunction (biology)

Abstract

fetched live from OpenAlex

Abstract: (299 words). The quest to model carbyne has been largely tackled through the design of increasingly longer polyynes. [n]Cumulenes are an alternative class of molecules to model carbyne. The major difference between polyynes and cumulene as model compounds, however, is that polyynes maintain strong BLA while cumulenes do not. The synthetic development of longer [n]cumulenes has been challenged by decreased stability relative to oligoynes. This study compares the persistence of tetraaryl[n]cumulenes as a function of the ortho-substituent(s) of aryl endgroups. A clear trend emerges in which aryl endgroups with bulkier alkyl ortho-substituents offer more persistent [n]cumulenes. The enhanced stability is consistent with combination of steric shielding and disrupted electronic communication between the endgroups and cumulenic framework. Kinetically stabilized odd [n]cumulenes of the series [n]otBu (n is an odd integer, n = 5, 7, 9, 11, and 13) are successfully synthesized. The longest derivatives, [11]otBu and [13]otBu, are studied in solution, and the electronic absorption properties are compared experimentally and computationally with polyynes. The terminal alkylidene groups of [n]cumulenes have significant effects on the optical properties and result in the observation of an additional optical state, S1, relative to oligoynes. Access to the S1 state in [n]cumulenes gives a lower fundamental optical energy gap (Eg) relative to oligoynes, although the intensity of S1 decreases as a function of length as the molecules transition from D2h to D∞h symmetry. The highest energy state of [n]cumulenes (S4) is fully allowed by symmetry at any length and shows a remarkable similarity to the analogous absorptions of polyynes. At infinite length, this state would be expected to dominate the spectra of both polyynes and cumulenes.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesInsufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.072
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.020
GPT teacher head0.229
Teacher spread0.210 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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