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Record W4414902965 · doi:10.1101/2025.10.02.25337214

Impact of Nocturnal Blood Pressure Patterns on BMI, Diabetes, and Cardiovascular Health: A Comprehensive Analysis

2025· preprint· en· W4414902965 on OpenAlexaff
Md. Delowar Hossain, Nawal Kalid, Jashnoor Kaur Bhatti, Sidharth Bhinder, Richard Siow, Yuichiro Yano, Raja B. Singh, Anmol Kapoor

Bibliographic record

VenuemedRxiv · 2025
Typepreprint
Languageen
FieldMedicine
TopicBlood Pressure and Hypertension Studies
Canadian institutionsUniversity of Calgary
Fundersnot available
KeywordsBlood pressureNocturnalBody mass indexAmbulatory blood pressureCohortDiabetes mellitusMasked HypertensionOverweight

Abstract

fetched live from OpenAlex

ABSTRACT Ambulatory Blood Pressure Monitoring (ABPM) provides valuable insights into a patient’s 24-hour blood pressure (BP) patterns, offering an enhanced assessment of cardiovascular health, particularly in relation to body mass index (BMI), diabetes, and menopausal status. This method provides a more comprehensive understanding of BP dynamics compared to traditional office-based measurements, assisting healthcare professionals with devising a more accurate assessment of a patient’s cardiovascular risk. ABPM is increasingly growing in adoption as a service in medical practices and pharmacies due to the numerous advantages. This retrospective cohort study analyzes 24-hour ABPM data from 5618 participants to investigate the relationship between nocturnal BP fluctuations found through ABPM with BMI, diabetes, hypertension in both male and female participants. It also investigates the relationship between nocturnal BP fluctuations and menopausal status in female participants. These conditions are studied to ultimately assess whether BP fluctuations are potentially connected to an increased risk of developing chronic conditions such as cardiovascular dysfunction. The ABPM nocturnal blood-pressure fluctuations are categorized within four distinct categories: normal dipping, non-dipping, reverse dipping, and extra dipping. The findings of this study show that 44.11% of participants exhibit hypertension, with most of these participants experiencing abnormal nocturnal blood pressure patterns. Increased BMI, particularly in overweight and moderately obese categories, was significantly associated with non-dipping patterns. In addition, the relationship between menopausal status for female participants and nocturnal dipping patterns, early morning hypertension and diabetes diagnoses are assessed. These findings underscore the importance of ABPM in detecting abnormal BP patterns and their associations with key health indicators, advocating for its broader integration in clinical settings.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.009
Threshold uncertainty score0.017

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.001
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.037
GPT teacher head0.313
Teacher spread0.276 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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