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Record W4414923311 · doi:10.3389/fonc.2025.1606568

Comparative short- and long-term outcomes of TOETVA, ETGUA, and COT in thyroid cancer: a propensity score-matched study

2025· article· en· W4414923311 on OpenAlexaboutno aff
Cong Bian, Zhenmeng Lin, Mingfang Yan, Chao Xie, Wen‐Chi Pan

Bibliographic record

VenueFrontiers in Oncology · 2025
Typearticle
Languageen
FieldMedicine
TopicThyroid and Parathyroid Surgery
Canadian institutionsnot available
FundersFujian Medical UniversityNatural Science Foundation of Fujian Province
KeywordsThyroidLymphQuality (philosophy)ThyroidectomyPropensity score matching

Abstract

fetched live from OpenAlex

Objective: This study aims to compare the short-term and long-term outcomes of three surgical approaches for thyroid cancer: Transoral Endoscopic Thyroidectomy Vestibular Approach (TOETVA), Gasless Unilateral Axillary Endoscopic Thyroidectomy (ETGUA), and Conventional Open Thyroidectomy (COT). Methods: A total of 466 thyroid cancer patients who underwent surgery were initially included. After propensity score matching (PSM), 318 patients were analyzed, with 106 patients in each group (TOETVA, ETGUA, and COT). The primary outcomes compared included surgical parameters (incision length, blood loss, operation time, lymph node dissection), postoperative inflammation (WBC, CRP, IL-6), postoperative complications, postoperative pain (Visual Analog Scale, VAS), scar assessment (Vancouver Scar Scale, VSS), wound satisfaction, costs, and quality of life (36-Item Short Form Health Survey, SF-36). Results: After matching, the operation time for TOETVA was longer than that for both ETGUA and COT. The number of lymph nodes dissected in ETGUA was fewer than in TOETVA and COT. There were no significant differences in postoperative complications, VAS scores, costs, or hospital stay among the three groups. On the first postoperative day, TOETVA and ETGUA showed higher levels of WBC and CRP than COT, but no significant differences were observed by day three. TOETVA had the shortest incision and the lowest VSS score. Wound satisfaction was significantly higher in both TOETVA and ETGUA compared to COT, with no significant difference between TOETVA and ETGUA. In terms of quality of life, some dimensions in TOETVA and ETGUA were higher than in COT. Each surgical approach has its own advantages and disadvantages. Conclusion: TOETVA demonstrated the shortest incision and the lowest VSS score, while both TOETVA and ETGUA showed the best wound satisfaction and specific domains of quality of life. However, TOETVA had the longest operation time, and ETGUA had the fewest lymph nodes dissected.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.012
Threshold uncertainty score0.701

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0020.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.065
GPT teacher head0.371
Teacher spread0.307 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2025
Admission routes1
Has abstractyes

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