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Record W4414939993 · doi:10.1177/2689288x251376991

Does Physical Fitness Prior to Traumatic Brain Injury Affect Recovery Outcomes? A Scoping Review of Human and Animal Research

2025· review· en· W4414939993 on OpenAlexafffund
Dean M. Cordingley, Izabella Marquez, Serena C. L. Buchwald, Frederick A. Zeiler

Bibliographic record

VenueNeurotrauma Reports · 2025
Typereview
Languageen
FieldMedicine
TopicTraumatic Brain Injury Research
Canadian institutionsUniversity of ManitobaUniversity of WinnipegPan Am ClinicManitoba Health
FundersNatural Sciences and Engineering Research Council of CanadaCanadian Institutes of Health ResearchResearch ManitobaHealth Sciences Centre Foundation
KeywordsSystematic reviewAffect (linguistics)Physical fitnessIntervention (counseling)MEDLINEVariety (cybernetics)Cochrane LibraryTraumatic brain injury

Abstract

fetched live from OpenAlex

The objective of this study was to identify whether physical fitness influences outcomes following traumatic brain injury (TBI) in humans and animals, and to highlight any knowledge gaps in the current literature. A search of EMBASE, MEDLINE, SCOPUS, BIOSIS, and Cochrane Libraries was performed on December 4, 2023 (from database inception), and a systematic scoping review of the resulting literature was conducted. The Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for scoping reviews was used for reporting the results. An online systematic review management system was used to remove all duplicates and for subsequent article screening. Following the removal of duplicates, the search identified 6,818 articles for screening, of which 10 articles met the inclusion/exclusion criteria and were included. One study was conducted in humans, while the remaining nine utilized murine models. The available literature is limited and has investigated a large variety of outcomes that were not consistent across studies. Additionally, the pre-TBI exercise intervention or fitness assessment method varied between the studies. With the current literature, it is not possible to draw conclusions regarding the effects of physical fitness level and outcomes following a TBI.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.006
metaresearch head score (Gemma)0.014
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch, Meta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Systematic review · Consensus signal: Systematic review
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.425
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0060.014
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0070.001
Bibliometrics0.0020.002
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0010.001
Research integrity0.0000.002
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.249
GPT teacher head0.543
Teacher spread0.294 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designSystematic review
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes2
Has abstractyes

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