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Record W4414944679 · doi:10.1139/cjpp-2025-0176

Association of blood pressure with nonalcoholic fatty liver disease defined by fatty liver index

2025· article· en· W4414944679 on OpenAlexvenueno aff
Anastasiya M. Kaneva, Evgeny R. Bojko

Bibliographic record

VenueCanadian Journal of Physiology and Pharmacology · 2025
Typearticle
Languageen
FieldMedicine
TopicLiver Disease Diagnosis and Treatment
Canadian institutionsnot available
Fundersnot available
KeywordsNonalcoholic fatty liver diseaseBlood pressureReceiver operating characteristicFatty liverPrehypertensionBody mass indexLiver disease

Abstract

fetched live from OpenAlex

Despite the known association between hypertension and nonalcoholic fatty liver disease (NAFLD), the cut-off values of blood pressure for identifying risk of NAFLD have not yet been determined. The aim of this study was to determine the diagnostic performance and optimal cut-off values of blood pressure for detecting NAFLD defined by fatty liver index (FLI). This cross-sectional study included 1227 participants aged 35-55 years. NAFLD was determined by FLI with a cut-off value of ≥60. Receiver operating characteristic (ROC) curve analysis was used to evaluate the diagnostic ability of blood pressure parameters for screening FLI-defined NAFLD and to determine their cut-off values. The results of this study showed that systolic blood pressure (SBP) and diastolic blood pressure (DBP) were significantly correlated with FLI values. The prevalence of NAFLD defined by FLI was 23.5% in men and 18.2% in women. The ROC curve analysis showed a good ability of blood pressure for the prediction of FLI-defined NAFLD. The optimal cut-off values of SBP and DBP were 136 and 88 mmHg in men and 137 and 85 mmHg in women, respectively. Thus, high-normal blood pressure is associated with the risk of NAFLD defined by FLI in both men and women.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.004
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.005
Threshold uncertainty score0.010

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.004
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.008
GPT teacher head0.248
Teacher spread0.240 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

Explore more

Same venueCanadian Journal of Physiology and Pharmacology→Same topicLiver Disease Diagnosis and Treatment→French-language works237,207→