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Record W4414976926 · doi:10.1016/j.wneu.2025.124528

Comparison of Anterior and Posterior Surgical Approaches for Cervical Ossification of the Posterior Longitudinal Ligament Stratified by Spinal Levels: A Systematic Review and Meta-Analysis

2025· review· en· W4414976926 on OpenAlexaff
Seyed Danial Alizadeh, Sepehr Khosravi, Farzin Farahbakhsh, Vali Baigi, Moein Khormali, Mohsen Hajiqasemi, Zahra Eskandari, Mahgol Sadat Hassan Zadeh Tabatabaei, Amirmahdi Khayyamfar, Mohammad-Rasoul Jalalifar, Sepehr Armaghan, Masoud Pourghahramani Koltapeh, Zahra Ghodsi, Michael G. Fehlings, Alexander R. Vaccaro, Vafa Rahimi‐Movaghar

Bibliographic record

VenueWorld Neurosurgery · 2025
Typereview
Languageen
FieldMedicine
TopicCervical and Thoracic Myelopathy
Canadian institutionsUniversity Health Network
FundersTehran University of Medical Sciences and Health Services
KeywordsLaminectomyOssification of the posterior longitudinal ligamentDysphagiaOssificationPosterior longitudinal ligamentCervical vertebraeSpinal fusion

Abstract

fetched live from OpenAlex

OBJECTIVE: To compare the outcomes of anterior and posterior surgical approaches for treating cervical ossification of the posterior longitudinal ligament across multiple spinal levels, including 1-2 spinal levels, ≥ 3 levels, or studies that operated on both spinal levels, called mixed spinal levels. METHODS: A search strategy using pertinent keywords was employed in the MEDLINE, Embase, Scopus, and Web of Science databases. Data on Modified Japanese Orthopaedic Association (mJOA) scores, radiographic outcomes, and complications were extracted. A random-effects meta-analysis, subgroup meta-analysis, and sensitivity analysis were performed. RESULTS: Among 13 included studies, the anterior approach was statistically associated with improved C2-C7 Cobb angle, mJOA scores between 6 and 12 months, and mJOA recovery rates at more than 12 months (mean difference: 5.87°, 0.49°, and 18.81°, respectively). Conversely, the laminoplasty (LAMP) approach was more effective at maintaining the range of motion in patients with ≥ 3 spinal levels operated on (mean difference: -1.78°). The odds ratio (OR) of C5 palsy revealed lower odds in anterior approaches following surgery at ≥ 3 spinal levels (OR: 0.24, 95% confidence interval: 0.15 to 0.37). The odds of dysphagia following surgery at mixed spinal levels were higher in anterior approaches (OR: 3.68, 95% confidence interval: 1.24 to 10.94). CONCLUSIONS: LAMP significantly preserved cervical range of motion. LAMP and laminectomy with fusion reduced dysphagia but increased C5 palsy. The anterior approach improved alignment and function, but the mJOA score and recovery rate were not clinically meaningful. Patient-specific characteristics should be taken into account when selecting the surgical approach.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.009
metaresearch head score (Gemma)0.021
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Meta-analysis · Consensus signal: Meta-analysis
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.021
Threshold uncertainty score0.049

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0090.021
Meta-epidemiology (narrow)0.0030.001
Meta-epidemiology (broad)0.0210.036
Bibliometrics0.0070.007
Science and technology studies0.0010.001
Scholarly communication0.0030.002
Open science0.0020.001
Research integrity0.0020.002
Insufficient payload (model declined to judge)0.0030.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.245
GPT teacher head0.408
Teacher spread0.163 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designMeta-analysis
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2025
Admission routes1
Has abstractyes

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