Mental health challenges and HIV status disclosure among children and adolescents living with HIV in Eastern Uganda
Bibliographic record
Abstract
Worldwide the prevalence of children and adolescents on antiretroviral therapy is increasing with the advancement in pediatric HIV care. However, this presents unique challenges associated with HIV status disclosure to the child or the adolescent without negatively affecting treatment outcomes. The primary objective of the study was to determine the prevalence of mental health challenges and their association with HIV status disclosure among children and adolescents seeking care at three pediatric HIV clinics in Eastern Uganda. This prospective cross-sectional study was conducted among children and adolescents aged 8-17 years. Disclosure was assessed using an adapted United States Agency for International Development -Academic Model Providing Access to Healthcare (AMPATH) disclosure questionnaire. Mental health outcomes (major depression, suicidality, generalized anxiety and alcohol use disorder) were evaluated using the Mini International Neuropsychiatric Interview (MINI-KID) questionnaire, stigma using the Internalized AIDS-Related Stigma Scale and social support using the Multidimensional Scale of Perceived Social Support. Prevalence of disclosure was determined as a proportion of participants in the study group who screened positive for disclosure as per the AMPATH disclosure questionnaire. Factors associated with mental health conditions were determined by running bi-variable and multivariable logistic regression models. Among the 326 children and adolescents enrolled, 23.3% (n = 76) had at least one mental health challenge (MHC). The prevalence of major depression was 14.1%, suicidality, 12.8%, generalized anxiety disorder, 8.59% and alcohol use disorder was 1.2%. MHCs were more common among children and adolescents living with HIV who had been disclosed of their HIV status. HIV status disclosure was a risk factor for both major depression (adjusted odds ratio (aOR) = 2.98, p = 0.018) and suicidality (aOR = 2.72, p = 0.031) but not generalized anxiety disorder. Older age (13-17 years) was a risk factor for major depression (aOR = 2.52, 95%, p = 0.001), while maternal caregiving (aOR = 0.42, p = 0.026) was protective. Generalized anxiety disorder (aOR = 7.44, p < 0.001) was a strong risk factor for suicidality while high perceived social support (aOR = 0.39, p = 0.024) was protective. Education level above primary (aOR = 2.80, p = 0.030) and internalized stigma (aOR = 1.67, p = 0.041) were risk factors for generalized anxiety disorder. Children and adolescents face unique mental health challenges associated with HIV status disclosure which calls for sociocultural appropriate interventions to bridge this gap.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.002 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.001 | 0.001 |
| Science and technology studies | 0.001 | 0.001 |
| Scholarly communication | 0.001 | 0.001 |
| Open science | 0.000 | 0.001 |
| Research integrity | 0.000 | 0.001 |
| Insufficient payload (model declined to judge) | 0.001 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".