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Development of an analytical method for the quantification of bromoform in milk using gas chromatography–mass spectrometry

2025· article· en· W4415002352 on OpenAlexafffund
Sophie Lamothe, Fleur Gagnon, Hassan Sabik, Marie‐Claude Gentès

Bibliographic record

VenueFood Chemistry · 2025
Typearticle
Languageen
FieldAgricultural and Biological Sciences
TopicMeat and Animal Product Quality
Canadian institutionsAgriculture and Agri-Food Canada
FundersAgriculture and Agri-Food Canada
KeywordsBromoformMethaneResidue (chemistry)Extraction (chemistry)Gas chromatographyMass spectrometryDetection limit

Abstract

fetched live from OpenAlex

Enteric methane production by ruminants contributes significantly to global greenhouse gas emissions. Seaweeds are rich in bromoform, which are known to strongly reduce methane emissions when included in animal feed. To ensure that seaweeds can be safely used for methane mitigation, there is a need to monitor bromoform residue in milk. The objective of this study was to develop and validate an analytical approach for quantifying bromoform in milk. QuEChERS-based extraction and clean-up with dispersive solid phase extraction were used followed by analysis with gas chromatography–mass spectrometry. The proposed method was validated: the limit of quantification (LOQ) was 0.21 μg L −1 , and recovery rates ranged from 86 % to 101 % with a precision <18.9 %. Twenty-two commercial milks were analyzed and contained bromoform residues at concentrations ranging from below the LOQ to 0.34 μg L −1 . This method is a reliable tool for monitoring the presence of bromoform in milk.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.002
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Methods · Consensus signal: Methods
Teacher disagreement score0.002
Threshold uncertainty score0.011

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0020.002
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0010.000
Science and technology studies0.0010.001
Scholarly communication0.0010.001
Open science0.0010.001
Research integrity0.0020.002
Insufficient payload (model declined to judge)0.0010.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.078
GPT teacher head0.329
Teacher spread0.251 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreMethods

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes2
Has abstractno

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