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Record W4415017234 · doi:10.1016/j.eclinm.2025.103559

Research priorities on physical-mental comorbidity in children and adolescents: an international consensus

2025· review· en· W4415017234 on OpenAlexafffund
Denan Jiang, Jiali Zhou, Yajie Zhu, Edimansyah Abdin, Tracie O. Afifi, Laura Helena Andrade, Rebecca Bendayan, Emma E Berkelbach van der Sprenkel, Ronny Bruffaerts, Ferrán Catalá-López, Ian Colman, Benjamin G. Druss, Laura Duncan, Nuša Farič, Erika D. Felix, Holly Foster, Shurong Lu, Hassan Mansour, Ruth Ann Marrie, Tanya Meade, Salima Meherali, Carles Muntaner, Yoko Nomura, Junko Okuyama, Susan Rees, Graham J. Reid, Janet U. Schneiderman, Dan J. Stein, Frederick W. Thielen, Wan Yee Winnie Tso, André O. Werneck, Xiaoyan Wu, Igor Rudan, Peige Song

Bibliographic record

VenueEClinicalMedicine · 2025
Typereview
Languageen
FieldHealth Professions
TopicChild and Adolescent Health
Canadian institutionsChildren’s Health Research InstituteLawson Health Research InstituteWestern UniversitySt. Michael's HospitalUniversity of AlbertaNova Scotia Health AuthorityMcMaster UniversityMcMaster Children's HospitalDalhousie UniversityHamilton Health SciencesManitoba HealthUniversity of OttawaUniversity of Manitoba
FundersCanadian Institutes of Health ResearchNational Natural Science Foundation of ChinaCanada Research ChairsPublic Health Agency of Canada
KeywordsComorbidityKnowledge translationGlobal healthMEDLINEPsychiatric comorbidityOutcomes researchConsensus conferenceChild health

Abstract

fetched live from OpenAlex

Physical-mental comorbidity in children and adolescents is an emerging global health concern, yet research remains fragmented and lacks a coordinated agenda. We conducted a global priority setting exercise using the Child Health and Nutrition Research Initiative method. A total of 134 research ideas were scored by 45 experts against five criteria: answerability, effectiveness, potential for paradigm shift, potential for translation and implementation, and impact on equity. The highest-ranked priorities focused on treatment strategies, early intervention, reducing disparities in care, and the role of schools and communities in supporting health. Comparative analyses revealed both shared and context-specific needs across income settings. This is the first global consensus on research priorities for child and adolescent physical-mental comorbidity and offers a strategic roadmap to guide future research and policy.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.003
metaresearch head score (Gemma)0.002
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow), Research integrity
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Other design · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.904
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0030.002
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0020.000
Bibliometrics0.0010.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0010.000
Research integrity0.0000.005
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.234
GPT teacher head0.601
Teacher spread0.367 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designOther design
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations4
Published2025
Admission routes2
Has abstractyes

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