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Record W4415042927 · doi:10.1016/j.jaacop.2025.10.001

Autism Diagnostic Assessments for Gender-Diverse Individuals: A Modified Delphi Study of Clinician Experts in the Fields of Autism and Gender Diversity

2025· article· en· W4415042927 on OpenAlexafffund
Kate Cooper, Anna I. R. van der Miesen, Meng‐Chuan Lai

Bibliographic record

VenueJAACAP Open · 2025
Typearticle
Languageen
FieldNeuroscience
TopicAutism Spectrum Disorder Research
Canadian institutionsHospital for Sick ChildrenUniversity of TorontoCentre for Addiction and Mental Health
FundersUniversity of BathCanadian Institutes of Health ResearchCentre for Addiction and Mental Health FoundationNational Institute for Health and Care ResearchCentre for Addiction and Mental Health
KeywordsAutismDelphi methodDiversity (politics)Gender diversityDelphiField (mathematics)

Abstract

fetched live from OpenAlex

Objective There is limited evidence-based guidance about how autism diagnostic assessments should be conducted for gender-diverse people. We aimed to integrate expert knowledge on key clinical considerations for these assessments. Method We conducted a modified Delphi study. World experts in the field ( N =21) were invited to complete two rounds of surveys. Survey One collected open-text responses about key clinical considerations when conducting diagnostic assessments, structured around the DSM-5-TR criteria for autism, across age-ranges. Experts were asked to rate the importance of each consideration they listed. A content analysis was conducted to synthesise and collate similar considerations, alongside descriptive statistics of importance ratings. Survey Two presented the resulting considerations and mean importance ratings, with experts re-rating their importance. Statements rated as at least ‘important' and that had a standard deviation of less than 1.0 were reported. Results Round one resulted in 65 individual statements, of which 37 met our definition for reporting. These statements, summarizing expert opinions, were categorised as being (1) general considerations for assessments, (2) linked to the DSM-5-TR autism criteria (A-E), or (3) practical considerations for working with the gender-diverse population. They highlighted areas to be considered during assessments, such as ways in which the features of autism may intersect with gender diversity, and practical considerations for increasing comfort and engagement of gender-diverse individuals undergoing an autism assessment. Conclusion The summary of expert opinions provides preliminary considerations for clinicians working in this field, and for researchers to use as hypotheses for empirical investigations.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.302
Threshold uncertainty score0.540

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0020.003
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.274
GPT teacher head0.460
Teacher spread0.186 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes2
Has abstractyes

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