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EVALUATING THE EFFICACY OF A VIRTUAl PAEDIATRIC ADVERSE DRUG REACTION CLINIC

2025· preprint· en· W4415051143 on OpenAlexaff
E. W. Hauck, Michael Rieder

Bibliographic record

Venuenot available
Typepreprint
Languageen
FieldPharmacology, Toxicology and Pharmaceutics
TopicPharmacy and Medical Practices
Canadian institutionsWestern University
Fundersnot available
KeywordsAdverse effectDrugAdverse drug reactionDrug reactionMEDLINE

Abstract

fetched live from OpenAlex

Adverse drug reactions (ADRs) are a common and significant cause of morbidity and mortality, yet access to specialized ADR services for children is limited. The purpose of this study was to evaluate the efficacy of, and satisfaction with, a virtual paediatric ADR clinic based in London, ON during the COVID-19 pandemic. This was done by extracting patient information from an online database and conducting brief satisfaction surveys with patient families and referring clinicians. We found that 225 ADRs were assessed virtually over three years, with an average referral time of 23 days and 43.6% of patients residing in distant rural and urban communities. Further testing (most commonly DPT, RAST, LTA) was recommended for 89.3% of patients. While a number of results are pending, 17.2% and 43.5% of tests ordered were positive and negative respectively. A high level of satisfaction was reported by patient families (95.0%) and referring physicians (93.3%) that responded to the survey. This study demonstrated the ability of a virtual clinic to efficiently assess and triage children with a suspected ADR and suggests that telemedicine is a feasible way to improve access to specialized ADR services for children.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.008
metaresearch head score (Gemma)0.005
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow), Research integrity, Insufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.704
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0080.005
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0010.001
Research integrity0.0010.005
Insufficient payload (model declined to judge)0.0050.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.296
GPT teacher head0.572
Teacher spread0.277 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designNot applicable
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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