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Record W4415055368 · doi:10.31083/ijp44192

Understanding the Opioid Overdose Crisis: A Comprehensive Bibliometric Analysis

2025· article· en· W4415055368 on OpenAlexaboutno aff
Tawfeeq Altherwi

Bibliographic record

VenueInternational Journal of Pharmacology · 2025
Typearticle
Languageen
FieldMedicine
TopicOpioid Use Disorder Treatment
Canadian institutionsnot available
Fundersnot available
KeywordsScopusOpioid overdoseThematic analysisCitationDrug overdoseMedical prescriptionBibliometricsCitation analysisOpioid

Abstract

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Background and Objective: Opioid overdose represents a critical public health issue that has attracted considerable research interest. Therefore, objective of this study aimed to conduct a comprehensive analysis of the opioid overdose research (OOR) landscape, performance, evolution, citation impact and changing research themes. Materials and Methods: A bibliometric analysis was performed on the OOR data published between, 1971 and 2024. Data were gathered from the Scopus database and analyzed using Bibliometrix and VOSviewer. Citation counts, prolific authors, top sources, and seminal publications were also identified. Thematic mapping was performed to aid the visualization of the major clusters in the OOR data. Results: The analysis included 13,971 authors who contributed to the OOR. Prolific authors, such as Walley, A.Y., and Green, T.C., made notable contributions. "Drug and alcohol dependence" emerged as the top source in the publications. The United States exhibited the highest research output, followed by Canada, the United Kingdom, and Australia. The average citation count per article was 22.44, indicating the impact and visibility of the research. Seminal publications have addressed critical topics including opioid prescription patterns, economic burden, medication-assisted therapies, and overdose prevention programs. Thematic mapping revealed clusters related to drug overdose, opioids, overdose prevention, toxicology, buprenorphine, and opioid use disorders. Conclusion: The findings showed an ongoing need for further studies on gap filling, such as long-term consequences, socioeconomic factors and inequalities, in addition to technology application and interdisciplinary collaboration. By focusing on new themes, as well as longitudinal studies, stakeholders can gain improved knowledge on opioid overdose problem-solving solutions that have been applied to victims and their communities, thereby improving outcomes.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Direct model labels (unvalidated)

Per-model category and study-design labels from the labeling rounds. They are machine output, unvalidated, and the disagreement between models ships as data. No study design here is MEDLINE-validated yet.

Model armCategoriesStudy designConfidence
gemmaBibliometrics
Domain: not available · Genre: Empirical
About the Canadian research system: no · About a Canadian topic: no
Observationallow
gptBibliometrics
Domain: not available · Genre: Empirical
About the Canadian research system: no · About a Canadian topic: no
Other designlow
models splitAgreement compares identical category sets and study designs across arms.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesBibliometrics
Consensus categoriesBibliometrics
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.505
Threshold uncertainty score0.997

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0350.024
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.063
GPT teacher head0.404
Teacher spread0.342 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Labeled directly by 2 models reading the full record.

Bibliometrics

The models disagree on parts of this classification; every voice is preserved in the section at the end of the page.

Study designObservational · Other design
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

Explore more

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