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Record W4415063698 · doi:10.1002/pne2.70015

Pain Measurement in Infants and Children With and at Risk for Intellectual Disabilities

2025· review· en· W4415063698 on OpenAlexaff
Morgan MacNeil, Britney Benoit, Timothy Disher, Aaron J. Newman, Marsha Campbell‐Yeo

Bibliographic record

VenuePaediatric and Neonatal Pain · 2025
Typereview
Languageen
FieldMedicine
TopicPediatric Pain Management Techniques
Canadian institutionsGovernment of Nova ScotiaSt. Francis Xavier UniversityNova Scotia Health AuthorityIzaak Walton Killam Health CentreDalhousie University
Fundersnot available
KeywordsIntellectual disabilityPain assessmentMedical diagnosisNeurotypicalMEDLINERisk assessmentDisadvantageSample (material)

Abstract

fetched live from OpenAlex

Standards of patient care require that comprehensive pain assessments be conducted at routine intervals. Infants and children with and at risk for intellectual disabilities, who are at high risk for experiencing pain, receive significantly less representation in the literature to inform pain measurement practice. The objectives of this review include (1) review and discuss the current literature surrounding pain measurement in infants and children with and at risk for intellectual disabilities, (2) define pain assessment tools, scales, and measures that are being used in infants and children with and at risk for intellectual disabilities, (3) discuss the strengths and limitations of the pain assessment tools, scales, and measures, (4) make recommendations for future pain research focused on this population. A narrative review of the literature regarding pain measures in infants and children with and at risk for intellectual disabilities was conducted using PubMed. A search strategy was created in consultation with a librarian scientist. There were no date limiters applied to the search. Pain measures can be classified as self-report, behavioral (e.g., cry, facial expressions), physiological (e.g., heart rate, biomarkers, oxygen saturation, respiratory rate), and neurophysiological (electroencephalogram, functional magnetic resonance imaging, near infrared spectroscopy). There is a considerable dearth in the literature surrounding pain measures and pain indicators in this population, along with small sample sizes and inconsistent findings reported across studies. Future research is needed to compare pain responses across different age groups and intellectual disability diagnoses to neurotypical peers.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.006
metaresearch head score (Gemma)0.009
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch, Meta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.938
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0060.009
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0010.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.021
GPT teacher head0.271
Teacher spread0.250 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designNot applicable
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2025
Admission routes1
Has abstractyes

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