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Record W4415085421 · doi:10.14423/smj.0000000000001888

Two Cases of Mistaken Identity: Neuroendocrine Tumors for Primary or Metastatic Breast Cancer

2025· article· en· W4415085421 on OpenAlex
Adnan Rajeh, Manaf Ubaidat, Priscilla Crivellaro, Daryl Ramsewak, Michael Sanatani

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

VenueSouthern Medical Journal · 2025
Typearticle
Languageen
FieldMedicine
TopicNeuroendocrine Tumor Research Advances
Canadian institutionsWestern University
Fundersnot available
KeywordsNeuroendocrine tumorsMetastatic breast cancerBreast cancerPathologicalPrimary tumorCA15-3Metastasis

Abstract

fetched live from OpenAlex

There are similarities between neuroendocrine tumors (NET) and primary breast cancers. A misdiagnosis can significantly affect prognosis and patient treatment plans, leading to potential catastrophic effects on patient care. In this study, we look at two cases in which NET was misdiagnosed as a primary breast cancer, in the breast in one case, and as metastatic breast cancer in the liver in the other case. The goals of this study were to highlight the pathological overlap between primary breast cancer with NET features and neuroendocrine tumors and the differences between their radiological appearances and to suggest steps to prevent this misdiagnosis from occurring, highlighting both the utility of informed clinical suspicion and timed imaging and pathology reviews.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.003
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesInsufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Case report · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.397
Threshold uncertainty score0.999

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.003
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.033
GPT teacher head0.391
Teacher spread0.358 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it