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Record W4415144780 · doi:10.7759/cureus.94542

Prevalence of Musculoskeletal Conditions in Heart Patients Undergoing Cardiovascular Rehabilitation Programs: A Systematic Review and Meta-Analysis

2025· review· en· W4415144780 on OpenAlexaboutno aff
Alessandra Straioto Salomão, Fernando Soares Piquione, Crystian B. Oliveira, Ana Clara Campagnolo Gonçalves Toledo

Bibliographic record

VenueCureus · 2025
Typereview
Languageen
FieldMedicine
TopicCardiac Health and Mental Health
Canadian institutionsnot available
Fundersnot available
KeywordsRehabilitationObservational studyDiseaseOsteoporosisMEDLINEEpidemiologyQuality of life (healthcare)Musculoskeletal disease

Abstract

fetched live from OpenAlex

Exercise-based cardiovascular rehabilitation is an essential strategy for managing cardiovascular diseases. However, some factors, such as musculoskeletal conditions, may limit exercise capacity and adherence. Although musculoskeletal conditions can lead to activity limitations and influence the strategies used in cardiovascular rehabilitation programs, their management and evaluation are often under-recognized. Knowledge of these conditions is important for interprofessional providers to adapt therapeutic care for this population. This study aimed to verify, through a systematic review and meta-analysis, the prevalence of musculoskeletal conditions in patients enrolled in cardiovascular rehabilitation programs. The search strategy was updated and last executed in May 2024 in the following electronic databases: MEDLINE, EMBASE, CINAHL, Web of Science, and SCOPUS. Observational studies that showed the prevalence of musculoskeletal conditions in patients with heart disease undergoing cardiovascular rehabilitation programs were eligible. To assess the risk of bias in the studies, we used the Newcastle-Ottawa Scale, and to check the overall quality of the evidence, we used the GRADE system. A total of 2,638 studies were screened, of which eight met the inclusion criteria and were rated as having moderate to high methodological quality. The prevalence of musculoskeletal conditions in patients enrolled in a cardiac rehabilitation program was 57.5%, CI 95%: 40.1-73.3; I²: 98%. Common musculoskeletal conditions were arthritis with a prevalence of 49.0%, CI 95%: 35.7-62.4; I²: 98%, musculoskeletal pain with a prevalence of 40.0%, CI 95%: 23.0-60.0; I²: 98%, and osteoporosis with a prevalence of 10.3%, CI 95%: 8.3-12.7; I²: 1%. In the studies included in this review, we found a high prevalence of musculoskeletal conditions. Future studies will be necessary to scrutinize and analyze whether the type, intensity, frequency, and duration of physical exercises proposed in cardiovascular rehabilitation programs can improve or worsen musculoskeletal conditions. These findings highlight the need to integrate musculoskeletal assessment and management into cardiac rehabilitation practice.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.016
metaresearch head score (Gemma)0.037
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Meta-analysis · Consensus signal: Meta-analysis
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.021
Threshold uncertainty score0.085

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0160.037
Meta-epidemiology (narrow)0.0020.002
Meta-epidemiology (broad)0.0210.045
Bibliometrics0.0080.010
Science and technology studies0.0010.001
Scholarly communication0.0040.002
Open science0.0020.002
Research integrity0.0020.002
Insufficient payload (model declined to judge)0.0030.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.045
GPT teacher head0.399
Teacher spread0.354 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designMeta-analysis
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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