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Record W4415166313 · doi:10.1101/2025.10.12.25337833

Effectiveness and Cost-effectiveness of Home-Based Occupational Therapy with Activity Monitoring for Daily Functioning of People Post-Stroke: Protocol for a Partially Randomised Usual Care Stepped-Wedge Trial

2025· preprint· en· W4415166313 on OpenAlexaboutno aff
Sanne Pellegrom, Margriet Pol, Ton Satink, Margo van Hartingsveldt, Johanna M. van Dongen, Gerben ter Riet, Bianca M. Buurman, Maud Graff

Bibliographic record

VenuemedRxiv · 2025
Typepreprint
Languageen
FieldMedicine
TopicStroke Rehabilitation and Recovery
Canadian institutionsnot available
FundersZonMw
KeywordsActivities of daily livingOccupational therapyRehabilitationIntervention (counseling)CoachingRandomized controlled trialProtocol (science)Geriatric rehabilitationActivity monitor

Abstract

fetched live from OpenAlex

Abstract Background Transitioning from a geriatric rehabilitation centre or hospital to home is challenging for persons post-stroke, as they must increase their ability to perform daily activities and self-manage their lives. Moreover, persons post-stroke exhibit more sedentary behaviour at home than during rehabilitation, which is detrimental to their health. The Occupational Therapy at Home E-Rehabilitation (OTHER) intervention aims to increase daily activities and self-management in persons post-stroke. OTHER involves in-person (online) coaching with information from activity monitoring. Here, we describe the design of a study investigating the (cost-)effectiveness of OTHER on the recovery of daily activities among older persons after stroke and evaluate its implementation process. Methods A partially cluster randomised stepped-wedge trial is conducted in nine geriatric rehabilitation centres and two hospitals, aiming to include 171 post-stroke participants (aged ≥ 60 years) who are starting (inpatient) rehabilitation to return home. The intervention group receives the OTHER intervention by an occupational therapist, starting at the institute and continuing at home. This intervention consists of activity monitoring to increase insight into movement behaviour, as well as coaching by occupational therapists on improving daily activities at home. This supports persons post-stroke in performing daily activities and increasing self-management. The control group receives care as usual. The primary outcome is the performance score of the Canadian Occupational Performance Measure, which measures a person’s perceived daily functioning at 6 months. A process evaluation will be conducted to assess the implementation process of the OTHER intervention during the research period. Discussion This trial is studying the effect of activity monitoring combined with home-based occupational therapy coaching for persons post-stroke. With this study, we aim to provide insight into the effectiveness and cost-effectiveness of the OTHER intervention compared to care as usual for persons post-stroke, and describe the process of implementation, which includes home-based geriatric rehabilitation. Trial registration ClinicalTrials.gov : NCT05855226 , and Organization’s Unique Protocol ID: 80-86900-98-022, registered may 11 th 2023

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.020
metaresearch head score (Gemma)0.022
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Non-randomized trial · Consensus signal: none
GenreCandidate signal: Protocol · Consensus signal: Protocol
Teacher disagreement score0.033
Threshold uncertainty score0.110

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0200.022
Meta-epidemiology (narrow)0.0060.003
Meta-epidemiology (broad)0.0130.009
Bibliometrics0.0030.002
Science and technology studies0.0020.003
Scholarly communication0.0030.003
Open science0.0030.002
Research integrity0.0050.005
Insufficient payload (model declined to judge)0.0330.005

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.045
GPT teacher head0.371
Teacher spread0.326 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNon-randomized trial
Domainnot available
GenreProtocol

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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Same venuemedRxiv→Same topicStroke Rehabilitation and Recovery→French-language works237,207→