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The contribution of lower limbs to Pelvic Tilt: A baseline and postoperative full-body analysis

2025· article· en· W4415270100 on OpenAlexaff
Marc Khalifé, Renaud Lafage, Bassel Diebo, Alan H. Daniels, Munish C. Gupta, Christopher P. Ames, Shay Bess, Douglas Burton, Khaled M. Kebaish, Michael P. Kelly, Han-Jo Kim, Eric O. Klineberg, Lawrence G. Lenke, Stephen Lewis, Peter G. Passias, Christopher I. Shaffrey, Justin S. Smith, Frank Schwab, Virginie Lafage

Bibliographic record

VenueGait & Posture · 2025
Typearticle
Languageen
FieldMedicine
TopicScoliosis diagnosis and treatment
Canadian institutionsToronto Western Hospital
FundersDePuy Synthes Spine
KeywordsSpinal deformityDeformityBaseline (sea)Magnitude (astronomy)Pelvis

Abstract

fetched live from OpenAlex

BACKGROUND: Pelvic tilt (PT) has been a parameter of interest in biomechanics of spinal deformity for decades. It remains unclear how patients achieve different values of PT pre- and postoperatively. RESEARCH QUESTION: This study aimed at assessing the relative contribution of hip extension, knee flexion and ankle extension to PT, factoring malalignment and hip osteoarthritis (OA). METHODS: This retrospective study included Adult Spinal Deformity (ASD) patients with preoperative full-body radiographs from a multicenter database, with a sub-analysis of patients with complete 1-year follow-up (1yFU). Age and PI-adjusted normative PT (NormPT) and offset from norm (OffPT) were calculated, as for sacro-femoral angle (SFA), knee flexion angle (KA) and ankle angle (AA). Multivariate linear regression models controlling for age, frailty, severe hip OA, pelvic incidence (PI), SFA, and KA were used to predict PT at baseline, and offset from NormPT. Another model was generated to predict PT change. RESULTS: 600 patients at baseline and 336 with 1yFU were included. Mean age was 61 ± 15, 70.2 % were females and 40 % were revision cases. At baseline, regression analysis revealed that 0.9° increase in hip extension (SFA) and a 0.6° increase in knee flexion (KA) amounted to 1° increase in PT. Knee and ankle contribution to PT significantly increased for while hip extension decreased as TPA augmented (p < 0.001). Patients with low deformity compensated with hip extension, while knee flexion was the largest contributor of PT in high deformity patients: 70.7 % (44.7 - 111.9). Median contribution of knee flexion to PT was larger for patients who presented hip OA. SIGNIFICANCE: This study demonstrated that PT is a phenomenon driven by extension of the hips and flexion of the knees and proposed values to predict PT from those two compensatory mechanisms. Magnitude of spinal deformity and hip OA alters the magnitude of SFA/KA contribution to PT.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.002
Threshold uncertainty score0.005

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.001
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.001
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.005
GPT teacher head0.285
Teacher spread0.280 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

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Citations0
Published2025
Admission routes1
Has abstractyes

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