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Record W4415273741 · doi:10.3389/fimmu.2025.1715204

Editorial: The immunological effects of respiratory viruses during pregnancy and breastfeeding

2025· editorial· en· W4415273741 on OpenAlexaff
Stella Liong, Kwok Ho Christopher Choy, Stavros Selemidis, Bahaa Abu-Raya, Domenico Umberto De Rose

Bibliographic record

VenueFrontiers in Immunology · 2025
Typeeditorial
Languageen
FieldMedicine
TopicCOVID-19 Impact on Reproduction
Canadian institutionsNova Scotia Health AuthorityIzaak Walton Killam Health CentreDalhousie University
Fundersnot available
KeywordsBreastfeedingPregnancyImmunityImmune systemVaccinationAcquired immune systemRespiratory systemFetus

Abstract

fetched live from OpenAlex

Pregnancy and the early postnatal period are marked by unique immunological adaptations that heighten susceptibility to infection, particularly from respiratory viruses. Dysregulation of maternal and fetal immunity during early gestation or soon after birth can have long-term health consequences. In summary, this research topic offers insights on how respiratory viral infections intersect between maternal and neonatal immunity, through various common themes. First, maternal-infant immunity is extremely dynamic and multifaceted, involving not just antibody transfer but also specific mediator signaling and adaptive breastmilk responses. Second, while maternal vaccination remains a critical strategy, variant-driven immune escape, that is very relevant to SARS-CoV-2, presents continued hurdles. Third, mechanistic findings at the cellular and molecular levels are consistent with population-level data on obstetric hazards, highlighting the field's translational value.Finally, the neurodevelopmental dimension emphasizes that the effects of maternal virus infection may persist well beyond the perinatal period. Other relevant research topics that might be of interest

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.013
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch, Meta-epidemiology (narrow), Research integrity
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Editorial · Consensus signal: Editorial
Teacher disagreement score0.068
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.013
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0010.000
Science and technology studies0.0000.001
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0020.002
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.009
GPT teacher head0.283
Teacher spread0.274 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designNot applicable
Domainnot available
GenreEditorial

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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