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Record W4415344901 · doi:10.1111/avj.70024

Canine gastric mucosal sarcoma: a novel tumour type

2025· article· en· W4415344901 on OpenAlex
SF Lane, A Ciavarella, B Remaj, KJ Deruddere, Lydia E Hambrook

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

aboutThe title or abstract carries a Canadian signal from the geographic lexicon.
no affNo Canadian affiliation: this work is invisible to an affiliation-only frame.
No Canadian affiliation. An affiliation-only frame, the usual design, would never have seen this work. It is one of the works that make the case for inverting the frame.

Bibliographic record

VenueAustralian Veterinary Journal · 2025
Typearticle
Languageen
FieldMedicine
TopicVeterinary Oncology Research
Canadian institutionsnot available
Fundersnot available
KeywordsSarcomaStomachMucosal lesionsPancreatic massMetastasisGastrointestinal tract

Abstract

fetched live from OpenAlex

BACKGROUND: Gastric neoplasia is uncommon in dogs accounting for ⟨1% of all neoplasms. Mesenchymal tumours arise from the muscularis layer of the gastric wall and represent 10-30% of canine gastric neoplasms. Gastric sarcomas arising from the muscularis layer of the stomach have not previously been reported. CASE REPORT: A 7-year-old, female spayed labrador was referred for investigation of chronic vomiting and regenerative anaemia. Abdominal imaging revealed a large solitary pedunculated mass (65 × 62 × 56 mm) within the pylorus and proximal duodenum. A Billroth I procedure was performed to resect the mass. Histopathology and immunohistochemistry were consistent with chronic hypertrophic pyloric gastropathy with atypical spindle cell proliferation confined to the mucosa. A Billroth II procedure was performed 5.5 months later due to local recurrence. A new omental nodule (12 × 13 mm) was identified 10 weeks later, which was surgically resected and confirmed a diagnosis of metastatic sarcoma. Adjuvant chemotherapy with doxorubicin was commenced. Repeat staging identified metastases to the pancreas and local tumour recurrence. The dog was euthanised due to clinical deterioration and biliary obstruction 20 months after the onset of clinical signs (14.5 months post Billroth I). CONCLUSION: This is the first report of a gastric mucosal sarcoma in a dog. Distinct from primary gastrointestinal sarcoma, which arises within the muscularis, the mass was confined within the gastric mucosal layer. The pedunculated nature of this mass made it amenable to surgical resection, but ultimately local recurrence was identified along with metastases. Pancreatic metastases have not previously been reported in gastrointestinal sarcomas.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow), Insufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.869
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.098
GPT teacher head0.401
Teacher spread0.303 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it