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Hippocampal–Cortical Networks Predict Conceptual versus Perceptually Guided Narrative Memory

2025· article· en· W4415368657 on OpenAlexafffund
C. Ferris, Rebecca Scheurich, Caroline Palmėr, Signy Sheldon

Bibliographic record

VenueJournal of Neuroscience · 2025
Typearticle
Languageen
FieldNeuroscience
TopicMemory and Neural Mechanisms
Canadian institutionsMcGill University
FundersNatural Sciences and Engineering Research Council of CanadaGRAMMY Museum FoundationCentre for Research on Brain, Language and Music
KeywordsHippocampal formationNarrativeEpisodic memoryEvent (particle physics)PerceptionSemantic memoryHippocampusEncoding (memory)Autobiographical memory

Abstract

fetched live from OpenAlex

Current theories of event memory propose distinct connections between the hippocampus and neocortical regions, particularly those within the default mode network (DMN) subsystems, to support processing different types of content in memory. It has been established that hippocampal connectivity supports integrating this disparate content into unified event memories, suggesting that changing the way that an event is described could change the underlying hippocampal neural network. To address this knowledge gap, we developed event narratives that described the same core story (e.g., grocery shopping) with identical central story details described with additional descriptive details that were conceptually or perceptually related to the story. Using fMRI, we established hippocampal connectivity patterns as a group of human participants ( N = 35, of any sex) encoded these narratives and then related these patterns to later memory for the narrative details. Consistent with prior work, we found that the conceptual narratives were associated with stronger anterior hippocampal connectivity to regions within the core and dorsomedial DMN subsystems, and a portion of this connectivity pattern predicted memory for the core story of the narrative. The perceptual narratives were selectively associated with anterior hippocampal connectivity to parietal and lateral temporal regions and regions outside the standard DMN, in relation to memory performance. These results provide new insights into hippocampal and DMN functional organization and how distinct neural components contribute differently to event memory.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.002
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.002
Threshold uncertainty score0.006

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.002
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.114
GPT teacher head0.351
Teacher spread0.237 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations4
Published2025
Admission routes2
Has abstractyes

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