MétaCan
Menu
Back to cohort
Record W4415430212 · doi:10.1302/1358-992x.2025.10.023

LONG-TERM RESULTS OF TOTAL ANKLE ARTHROPLASTY VERSUS ANKLE ARTHRODESIS: A FOLLOW-UP COFAS STUDY

2025· article· en· W4415430212 on OpenAlexaboutno aff
T Bala, Mark Glazebrook, Murray J. Penner, Timothy R. Daniels, Alastair Younger, Peter Dryden, Kevin Wing

Bibliographic record

VenueOrthopaedic Proceedings · 2025
Typearticle
Languageen
FieldMedicine
TopicFoot and Ankle Surgery
Canadian institutionsnot available
Fundersnot available
KeywordsAnkleAnkle replacementAnkle arthrodesisArthrodesisInformed consentOrthopedic surgeryArthroplastyCohort

Abstract

fetched live from OpenAlex

The aims of our current paper are to update the long term (minimum 10 year follow-upp) clinical outcomes of Total Ankle Replacement (TAR) and Ankle Arthrodesis (AA) in our original prospective, multicentre cohort of ankle arthritis patients with validated scoring instruments The Canadian Orthopaedic Foot and Ankle Society (COFAS) multicenter Ankle Arthritis Outcome Study was established in January 2003 and includes four study centers: Dalhousie University/Queen Elizabeth II Health Sciences Center, University of Toronto/St. Michael's Hospital, University of British Columbia/St. Paul's Hospital, and Vancouver Island Health Authority. This study was approved by the local hospital ethics boards. All patients provided informed consent for study enrollment and for the surgical procedure prior to questionnaire administration. Patients enrolled in this study constitute a subgroup of the COFAS Prospective Ankle Reconstruction Database. This database includes all patients with symptomatic end-stage ankle arthritis of various etiologies who had undergone an unsuccessful trial of nonoperative treatment, gave informed consent for database enrollment, and were treated with total ankle replacement or ankle arthrodesis by one of six subspecialty-trained orthopaedic surgeons at the four centers. Inclusion in the present study required skeletal maturity, a complete preoperative data set, and ability and willingness to give informed consent. Exclusion criteria were substantial osteonecrosis of the talus, prior ankle arthrodesis or arthroplasty, active or prior infection, Charcot arthropathy, and obesity (a body mass index [BMI] of >35 kg/m2). The final decision regarding the surgical treatment selection (ankle replacement or arthrodesis) was reached by consensus between the surgeon and patient. Arthrodesis was recommended for younger patients and patients with comorbidities that compromised soft-tissue healing (e.g., diabetes or current smoking). Ankle replacement was recommended in patients who were sixty-five years of age or older. Patient assessments were completed by the orthopaedic surgeon preoperatively, at one year following surgery, and annually thereafter. Patient demographics, comorbidities, and diagnoses were recorded preoperatively. Operative details were collected prospectively with use of the Halifax Joint Replacement Registry Form, which was developed for the COFAS database. Clinical outcomes were recorded preoperatively and at each follow-up visit with use of the Foot and Ankle Follow-up Questionnaire developed by a coalition of ten orthopaedic associations, including the American Academy of Orthopaedic Surgeons. This questionnaire includes the Ankle Osteoarthritis Scale (AOS) and the Short Form-36 (SF-36) Standard Version 2.0 Health Survey[2]. Data collected at each study site were transferred to the central data site at the Queen Elizabeth II Health Sciences Center in Halifax, Nova Scotia, Canada. AA patients are less likely to have a reoperation- 29% vs 43% in TAR- (P=0.02). AA patients are more likely to have hardware removal − 14% vs 2% in TAR (P<0.01). TAR patients had a rate of implat failure of 10%. TAR patients had significantly better improvements in AOS disability and pain when comparing RAW scores but when adjusted for age, sex, inflammatory disease, diabetes, BMI and pre-operative outcome scores- there was no statistical difference betwee the two groupsClinical outcomes of TAA & AA Similar when adjusted for comorbidities. Reoperation rates higher for TAA.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.032
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.023
GPT teacher head0.283
Teacher spread0.260 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

Explore more

Same venueOrthopaedic ProceedingsSame topicFoot and Ankle SurgeryFrench-language works237,207