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Record W4415434980 · doi:10.1016/j.jaccas.2025.105731

Massive Anterior STEMI Due to Essential Thrombocythemia Leading to Urgent Thrombocytapheresis

2025· article· en· W4415434980 on OpenAlexaff
Alexis V Rioux, Laurence Morin, Mathieu Bernier, Anthony Poulin

Bibliographic record

VenueJACC Case Reports · 2025
Typearticle
Languageen
FieldMedicine
TopicMyeloproliferative Neoplasms: Diagnosis and Treatment
Canadian institutionsCentre hospitalier universitaire de QuébecInstitut universitaire de cardiologie et de pneumologie de Québec
Fundersnot available
KeywordsEssential thrombocythemiaMyocardial infarctionDiseaseMEDLINEFibrinolytic therapyFibrinolytic agent

Abstract

fetched live from OpenAlex

BACKGROUND: Myocardial infarction in essential thrombocythemia (ET) is a rare but severe complication of this myeloproliferative disorder, occurring in approximately 2% to 3% of the population. CASE SUMMARY: /L on admission, justifying prompt thrombocytapheresis in the coronary care unit. DISCUSSION: In acute symptomatic thrombohemorrhagic complications, the American Society for Apheresis designates thrombocytapheresis as a Class II recommendation. This case describes the novel use of thrombocytapheresis in the setting of anterior STEMI with ET. TAKE-HOME MESSAGES: STEMI complicating acutely decompensated ET is life threatening, and early thrombocytapheresis should be considered in select patients. This case demonstrates the potential benefit of more aggressive cytoreductive therapy in patients with ET and underlying cardiovascular risk factors.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow), Insufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Case report · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.677
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.015
GPT teacher head0.322
Teacher spread0.307 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designCase report
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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