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The Cardiac Na <sup>+</sup> ‐Ca <sup>2+</sup> Exchanger

2002· article· en· W4415456504 on OpenAlexaff
Larry V. Hryshko

Bibliographic record

VenueComprehensive physiology · 2002
Typearticle
Languageen
FieldMedicine
TopicCardiac electrophysiology and arrhythmias
Canadian institutionsUniversity of ManitobaSt. Boniface Hospital
Fundersnot available
KeywordsSodium–hydrogen antiporterIon exchangeAnion exchangerSodium-calcium exchangerSodium

Abstract

fetched live from OpenAlex

Abstract The sections in this article are: A Brief Historical Perspective and Prelude to the Review Physiological Role of The Cardiac Na + ‐Ca 2+ Exchanger Reverse Na + ‐Ca 2+ Exchange as A Trigger for SR Ca 2+ Release Digitalis Effects Immunolocalization Transport Properties Stoichiometry Transport Mechanism Turnover Rates and Exchanger Density Ion Selectivity Temperature Dependence Molecular Biology of the Na + ‐Ca 2+ Exchanger The Prototypical Canine Cardiac Na + ‐Ca 2+ Exchanger The Exchanger Superfamily Topology of the Na + ‐Ca 2+ Exchanger The Calx‐α and Calx‐β Repeats Alternative Splicing of Na + ‐Ca 2+ Exchangers Regulation of Na + ‐Ca 2+ Exchange Ionic Regulation Structure–Function Relationships of Ionic Regulation Regulation by Phosphorylation Regulation by PIP 2 Regulation by pH Cytoskeletal Interactions Pharmacology of Na + ‐Ca 2+ Exchange The Exchanger Inhibitory Peptide, XIP Other Peptide Inhibitors KB ‐R7943 Other Inhibitors Studies in Transgenic Mice Adenoviral Transfection of Na + ‐Ca 2+ Exchange Proteins Antisense Oligonucleotides Frequency‐Dependent Behavior of Na + ‐Ca 2+ Exchange Developmental Changes Species Differences Pathophysiological Alterations in Na + ‐Ca 2+ Exchange Contribution of Na + ‐Ca 2+ Exchange to Cardiac Injury Alterations in Na + ‐Ca 2+ Exchange Levels Summary

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow), Insufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.249
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0000.000
Science and technology studies0.0010.001
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0010.003

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.022
GPT teacher head0.255
Teacher spread0.232 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designNot applicable
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2002
Admission routes1
Has abstractyes

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