Concomitant Cardiac Transthyretin Amyloidosis and Coronary Artery Disease---Imaging Features and Pitfalls
Bibliographic record
Abstract
The coexistence of coronary artery disease (CAD) and transthyretin cardiac amyloidosis (ATTR-CM) is increasingly recognized in clinical practice, especially in older adults. Although each condition has distinct pathophysiologic and imaging features, their association could be challenging for interpretation of imaging and diagnosis. This report presents a series of clinical cases that illustrate multimodality imaging findings in patients with coexisting CAD and ATTR-CM. It highlights the unique and overlapping features seen on echocardiography, cardiac magnetic resonance imaging, nuclear imaging, and coronarography. Special attention is given to diagnosis challenges that arise when these conditions coexist, and to the value of recognizing atypical findings of both CAD and ATTR-CM. The objectives of this report are to: 1) raise awareness of the possibility of ATTR-CM in patients with known CAD; and 2) discuss several specific multi-imaging features and specific findings encountered in clinical cases with concomitant CAD and ATTR-CM.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".