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Record W4415544310 · doi:10.1093/ageing/afaf309

Does predicting who will fall tomorrow tell you who is frail today?

2025· article· en· W4415544310 on OpenAlexaff
Hugh Logan Ellis, Kenneth Rockwood

Bibliographic record

VenueAge and Ageing · 2025
Typearticle
Languageen
FieldMedicine
TopicFrailty in Older Adults
Canadian institutionsNova Scotia Health AuthorityDalhousie University
Fundersnot available
KeywordsPerspective (graphical)Complement (music)WeightingTest (biology)PopulationMEDLINE

Abstract

fetched live from OpenAlex

A frequently raised question about frailty indices is whether certain variables should be weighted more heavily than others. In this commentary, we outline some of the pros and cons of weighting. Weighting can improve prediction of outcomes, but it also carries risks: underestimating the effects of existing interventions, prioritising factors that may not align with classical frailty phenotypes, and the risk that a model will not predict outcomes in the same way in a new population as it did in the one it was trained on. We offer an alternative perspective that frailty indices need not be seen only as prediction tools. Used as latent measures of health, they can support and complement clinical assessment. The true test of any data-derived frailty measure should be whether clinicians find it helpful in practice and whether its use can reduce the rate of adverse outcomes in a randomised controlled trial.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.441
Threshold uncertainty score0.540

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.009
GPT teacher head0.254
Teacher spread0.244 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations2
Published2025
Admission routes1
Has abstractyes

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