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Record W4415559389 · doi:10.1101/2025.10.25.684525

Influence of STDP rule choice and network connectivity on polychronous groups and cell ensembles in spiking neural networks

2025· preprint· W4415559389 on OpenAlexaff
Derek Arthur, Eric Albers, Masami Tatsuno

Bibliographic record

VenuebioRxiv (Cold Spring Harbor Laboratory) · 2025
Typepreprint
Language
FieldNeuroscience
TopicNeural dynamics and brain function
Canadian institutionsUniversity of Lethbridge
Fundersnot available
KeywordsSpiking neural networkArtificial neural networkHippocampal formationEncoding (memory)Spike-timing-dependent plasticityPattern recognition (psychology)

Abstract

fetched live from OpenAlex

Abstract Spike-timing dependent plasticity plays an important role in how biological neural networks modify themselves with experience. However, the relationship between STDP and memory is not fully understood. Previously, an important advancement in understanding the relationship between spike-timing dependent plasticity (STDP) and memory was made through cortical simulations. The proposed memory items, polychronous groups (PGs), combined the network anatomy with precise spike-timing relationships between the connected cells of the network. However, there are some challenges with this previous work. It is unclear how different STDP rules would impact the PG results and if the PG results are complementary with purely spike-pattern defined memory items called cell ensembles (CEs). Lastly, it is unclear how these results are affected by changes in network connectivity. We address these challenges by comparing the PGs and CEs detected in spiking neural network simulations of cortical and hippocampal CA1 networks with two different STDP rule implementations. We show that the PG and CE results differ greatly for the two different STDP rules and for the cortical and CA1 networks. Our results show an important disconnect between anatomically defined and spike-pattern defined memories in spiking neural network simulations illustrating that care must be taken when drawing conclusions on the relationship between STDP and memory in simulation studies.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.005
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Simulation or modeling · Consensus signal: Simulation or modeling
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.002
Threshold uncertainty score0.004

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.005
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.001
Scholarly communication0.0010.001
Open science0.0010.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.010
GPT teacher head0.213
Teacher spread0.203 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designSimulation or modeling
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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