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Record W4415572392 · doi:10.1021/acsami.5c13366

Dynamics of an Artificial Tear Film on Contact Lenses in Response to a Moving Force Mimicking Fingertip Application

2025· article· en· W4415572392 on OpenAlexafffund
Surjyasish Mitra, Vamika Kapur, Lyndon Jones

Bibliographic record

VenueACS Applied Materials & Interfaces · 2025
Typearticle
Languageen
FieldMedicine
TopicOcular Surface and Contact Lens
Canadian institutionsNational Institute for NanotechnologyUniversity of Waterloo
FundersNatural Sciences and Engineering Research Council of Canada
KeywordsContact lensDynamics (music)WettingReflection (computer programming)Thin filmLens (geology)Contact area

Abstract

fetched live from OpenAlex

Globally, it is estimated that more than 140 million people wear contact lenses. As a result, users demonstrate varying levels of dexterity and consistency when inserting lenses, often requiring fine adjustments. Moreover, the diverse structure and quality of individuals' precorneal tear films lead to different tear film responses under various insertion conditions. In this work, we mimic such tear film dynamics using a force probe coupled with reflection interference contrast microscopy. We use an in-house prepared artificial tear film solution that mimics human tear film composition deposited on commercially available soft contact lenses. The probe is used to replicate contact forces that resemble the pressure and motion of a human fingertip during lens insertion. Our findings reveal that contact-induced deformations and resulting film morphologies are sensitive to the volume, i.e., thickness of the tear film: from localized wetting ridges with memory effects for thicker films to traveling deformations with permanent wrinkling for thinner films. In extremely thin films, we observe that film evaporation dominates over contact-driven dynamics, although mobile contact forces can locally reverse rupture spots in the tear film.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.002
Threshold uncertainty score0.005

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.011
GPT teacher head0.278
Teacher spread0.267 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2025
Admission routes2
Has abstractyes

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