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Record W4415622168 · doi:10.1097/gox.0000000000007181

Elysee Exosome Versus Cellbooster Lift in Oral Wound Healing

2025· article· en· W4415622168 on OpenAlexaff
Noury Adel, Nenad Stankovic, Amira Gindi, Jack Kolenda, Natalia Mikhaylova, Tamar Miladze, Gerardo Cervantes, Alyaa Ragaei, Lamiaa M. Shawky, Mona Abdallah Sabry

Bibliographic record

VenuePlastic & Reconstructive Surgery Global Open · 2025
Typearticle
Languageen
FieldMedicine
TopicOral health in cancer treatment
Canadian institutionsUniversity of Toronto
Fundersnot available
KeywordsMicrovesiclesExosomeWound healingRegeneration (biology)Lift (data mining)Oral mucosa

Abstract

fetched live from OpenAlex

Background: The objective of this study was to evaluate the efficacy of injecting Elysee exosomes or Cellbooster Lift in promoting the healing of oral mucosal wounds. Methods: Thirty-six adult Wistar Albino rats were randomly divided into 3 groups. Group 1 served as the control group and underwent a scalpel incision in the oral mucosa without any intervention. Group 2 received an injection of Cellbooster Lift immediately after the incision, whereas group 3 was treated with Elysee exosomes. Biopsy samples were collected at baseline, as well as on the 7th and 14th postoperative days, for histological analysis. Hematoxylin and eosin staining was used to assess epithelial regeneration, whereas Masson trichrome staining was utilized to evaluate collagen formation and granulation tissue organization. Results: Both the Cellbooster Lift and Elysee exosome-treated groups showed improvements in wound healing compared with the control group. Both treatments accelerated healing, evidenced by increased collagen deposition and well-organized granulation tissue. Although the clinical outcomes were comparable between the Cellbooster Lift and Elysee exosome groups, histological analysis revealed that exosomes led to advanced epithelial regeneration and collagen formation, indicating their enhanced efficacy in promoting wound recovery. Conclusions: The injection of either Elysee exosomes or Cellbooster Lift enhanced the healing of oral mucosal wounds, with both treatments showing clinically similar improvements in recovery and tissue regeneration. However, histologically, exosomes demonstrated acceptable results, particularly in epithelial regeneration and collagen formation. These findings suggest that both therapies could be effective for oral wound healing, with exosomes offering an enhanced regenerative potential.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.064
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.067
GPT teacher head0.375
Teacher spread0.308 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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