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Vaping and Early Periodontal Damage in Teens: Associations with Community Periodontal Index Scores and Salivary Inflammatory Markers

2025· article· W4415668236 on OpenAlexaff
Abdulrahman Awad, Adam Friday

Bibliographic record

VenueJournal of AI-powered medical innovations. · 2025
Typearticle
Language
FieldDentistry
TopicOral microbiology and periodontitis research
Canadian institutionsRobarts Clinical TrialsWestern University
Fundersnot available
KeywordsSalivaPeriodontitisPeriodontal diseaseOral healthRisk factorClinical attachment lossInflammationDental plaque

Abstract

fetched live from OpenAlex

Electronic cigarette (e-cigarette) use has grown dramatically among adolescents, and there has been growing concern about the possible impact on oral and periodontal health. Although the perceived risks of vaping are less than conventional smoking, e-cigarette aerosols contain nicotine, aldehydes, and metal particulates which have the potential to change the oral microenvironment and inflammatory pathways. This study set out to find if e-cigarette use is associated with sub-clinical periodontal changes in high-school students by using Community Periodontal Index (CPI) scores and salivary inflammatory biomarkers as indicators of periodontal changes. A cross-sectional analytical design was used among adolescents aged 14-18 years old adapted into vapers and non-vapers. Clinical oral evaluations were performed by CPI, and the saliva samples were examined for interleukin (IL)-1v, IL-6 and tumor necrosis factor-alpha (TNF-a) levels using enzyme-linked immunosorbent assay (ELISA). Preliminary findings from similar studies have shown higher CPI scores with significantly higher salivary cytokine concentrations in adolescent e-cigarette users than in their non vaping counterparts suggesting the development of early periodontal inflammation before overt clinical disease. These results emphasize vaping as a possible risk factor for early changes in the periodontal tissues of the adolescent and recommend early detection, public health education and preventive measures in school-based oral health programs.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.005
metaresearch head score (Gemma)0.003
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow), Research integrity
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.007
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0050.003
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0020.002
Science and technology studies0.0010.002
Scholarly communication0.0010.001
Open science0.0010.001
Research integrity0.0010.007
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.014
GPT teacher head0.309
Teacher spread0.295 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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