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Record W4415678673 · doi:10.1093/nar/gkaf1110

TYGS and LPSN in 2025: a Global Core Biodata Resource for genome-based classification and nomenclature of prokaryotes within DSMZ Digital Diversity

2025· article· en· W4415678673 on OpenAlexfundno aff
Heike M. Freese, Jan P. Meier‐Kolthoff, Ayorinde O. Afolayan, Markus Göker

Bibliographic record

VenueNucleic Acids Research · 2025
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicGenomics and Phylogenetic Studies
Canadian institutionsnot available
FundersCanadian Patient Safety Institute
KeywordsNomenclatureInteroperabilityResource (disambiguation)TaxonGenomeDiversity (politics)Systematics

Abstract

fetched live from OpenAlex

The List of Prokaryotic names with Standing in Nomenclature (LPSN, https://lpsn.dsmz.de/) is an authoritative, expert-curated resource on prokaryotic nomenclature. Its sister database, the Type (Strain) Genome Server (TYGS, https://tygs.dsmz.de/), is a high-throughput platform for genome-based taxonomy. Here we present updates to these two platforms. New tools include improved interoperability with other DSMZ Digital Diversity databases, as well as easy-to-use query and access functions, and more comprehensive submission forms. The database content has expanded considerably, particularly through the inclusion of thousands of cyanobacterial names and the compilation of the List of Recommended Names for bacteria of medical importance (LoRN). LPSN now contains over 59 000 taxon names, and over 23 500 genome sequences have been added to TYGS. LPSN and TYGS have been updated to incorporate and reflect changes to the official rules governing prokaryotic nomenclature, as ratified by the International Committee on Systematics of Prokaryotes (ICSP) in recent years.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.008
metaresearch head score (Gemma)0.012
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Software · Consensus signal: none
Teacher disagreement score0.032
Threshold uncertainty score0.107

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0080.012
Meta-epidemiology (narrow)0.0020.001
Meta-epidemiology (broad)0.0020.001
Bibliometrics0.0120.017
Science and technology studies0.0010.001
Scholarly communication0.0060.006
Open science0.0030.007
Research integrity0.0020.003
Insufficient payload (model declined to judge)0.0320.042

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.057
GPT teacher head0.330
Teacher spread0.273 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreSoftware

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations51
Published2025
Admission routes1
Has abstractyes

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