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Record W4415685569 · doi:10.3389/fphys.2025.1711795

Meeting report: the inaugural muscle biology and cachexia conference at the University of Houston, May 18-20, 2025, Houston, Texas, USA

2025· article· en· W4415685569 on OpenAlexaboutno aff
J.-Y. Chen, Marco Brotto, Radbod Darabi, Ashok Kumar

Bibliographic record

VenueFrontiers in Physiology · 2025
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicMuscle Physiology and Disorders
Canadian institutionsnot available
Fundersnot available
KeywordsCachexiaCancer cachexiaPharmacySkeletal muscleMuscle proteinMuscle massExperimental biologyDrug discovery

Abstract

fetched live from OpenAlex

In May 2025, the University of Houston (UH) hosted the inaugural Muscle Biology and Cachexia conference, organized by Drs. Ashok Kumar and Radbod Darabi. The conference attracted nearly 300 participants, including established scientists, early-career researchers, and students from across the United States, Canada, Italy, Singapore, and Turkey. Research was presented through a combination of oral presentations and poster sessions. The conference was driven by the increasing interest in skeletal and cardiac muscle biology and cancer cachexia among institutions at the Texas Medical Center and surrounding universities. It served as a platform to promote knowledge exchange and foster collaboration within this growing scientific community. The conference was supported by the UH College of Pharmacy (UHCOP), Division of Research (DOR), Drug Discovery Institute (DDI), and the Department of Pharmacological and Pharmaceutical Sciences (PPS). In conjunction with the conference, UH announced the formation of the Institute of Muscle Biology and Cachexia (IMBC). The IMBC aims to strengthen collaborative research efforts and enhance understanding of the molecular and signaling pathways that regulate muscle physiology and disease.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Editorial · Consensus signal: Editorial
Teacher disagreement score0.220
Threshold uncertainty score0.737

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0020.001
Meta-epidemiology (narrow)0.0020.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0010.000
Science and technology studies0.0020.000
Scholarly communication0.0030.001
Open science0.0010.002
Research integrity0.0020.003
Insufficient payload (model declined to judge)0.2200.080

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.009
GPT teacher head0.240
Teacher spread0.232 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreEditorial

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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