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Personality traits and craving in patients undergoing alcohol withdrawal treatment

2025· article· en· W4415687932 on OpenAlexaboutno aff
Anne-Laure Virevialle, Benjamin Calvet, Murielle Girard, Mirvat Hamdan-Dumont, Brigitte Plansont, Aurélie Lacroix, Philippe Nubukpo

Bibliographic record

VenueJournal of Psychiatric Research · 2025
Typearticle
Languageen
FieldMedicine
TopicSubstance Abuse Treatment and Outcomes
Canadian institutionsnot available
Fundersnot available
KeywordsCravingBig Five personality traitsPersonalityAlcoholAlcohol use disorderAlcohol withdrawal syndromeRelapse prevention

Abstract

fetched live from OpenAlex

BACKGROUND: Alcohol use disorder (AUD) is a public health problem in France. Links between personality dimensions and AUD have already been established, but few studies focused on individuals seeking alcohol withdrawal. The main objective of the study was to describe the personality profile of patients seeking alcohol detoxification in a complex residential care unit. The secondary objective was to investigate the relationship between personality dimensions and alcohol craving. METHOD: The observational longitudinal exploratory study included 88 patients with AUD who were hospitalized during alcohol withdrawal treatment. Personality dimensions (125-item Temperament and Character Inventory, TCI), alexithymia (French scale for assessing alexithymia), craving (the Obsessive Compulsive Drinking Scale), anxiety (the Hamilton Anxiety Rating Scale), depressive symptoms (the Beck Depression Inventory) and cognitive dysfunction (the Montreal Cognitive Assessment) were assessed using the specified instruments at the time of withdrawal and 3 months later. Carbohydrate Deficient Transferrin and Brain-Derived Neurotrophic Factor (BDNF) levels were also measured at baseline and 3 months later. RESULTS: Among 76 patients assessed, 29 relapsed at 3 months. Relapsers showed higher novelty-seeking (mean ± SD = 63.2 ± 11.4 vs. 54.6 ± 10.8, p = 0.011), higher self-directedness (70.3 ± 9.1 vs. 63.0 ± 8.7, p = 0.009), and lower harm avoidance (48.7 ± 9.8 vs. 57.9 ± 10.5, p = 0.015). Logistic regression identified novelty-seeking as the strongest predictor of relapse (OR = 1.06, 95 % CI [1.01-1.11], p = 0.025). CONCLUSION: High novelty-seeking emerged as the main predictor of relapse three months after withdrawal. Although self-directedness appeared elevated in relapsers, this likely reflects transient self-regulation fostered by inpatient treatment rather than long-term resilience. Considering personality profiles in early recovery could help tailor relapse-prevention strategies in alcohol use disorder.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.014
Threshold uncertainty score0.311

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.054
GPT teacher head0.398
Teacher spread0.344 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

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Citations0
Published2025
Admission routes1
Has abstractyes

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