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23 Evaluating the efficacy of low-carbohydrate dietary interventions in type 2 diabetes management: results from the modality airedale, wharfedale and craven (AWC) and modality wokingham diabetes reversal programmes

2025· article· en· W4415702123 on OpenAlexaff
Sarah Armes, Jenneffer Tibas, Helen Rutherford, Sumantra Ray

Bibliographic record

Venuenot available
Typearticle
Languageen
FieldMedicine
TopicDiet and metabolism studies
Canadian institutionsUniversity of Alberta
Fundersnot available
KeywordsType 2 diabetesModality (human–computer interaction)Treatment modalityDiabetes mellitusModalities

Abstract

fetched live from OpenAlex

Background Type 2 Diabetes Mellitus (T2DM) is a global health concern, leading to serious complications and increased morbidity and mortality. This study explores the outcomes of two Modality Partnership diabetes management programmes: Modality AWC and Modality Wokingham Diabetes Reversal Programme (DRP).Methods The Modality Airedale, Wharfedale and Craven (AWC) Programme is a 3-month initiative for patients with T2DM, led by a general practitioner (GP) and a Low-Carb Health Coach Champion. The Modality Wokingham DRP is a 12-month, repeatable, virtual coach-led programme delivered via a smartphone app. It includes weekly coaching and three GP-led group education sessions. Both programmes monitor participants’ blood pressure, weight, HbA1c, and lipid levels, with additional liver and renal function tests as needed. The Modality Wokingham programme also gathered data from the NHS’s Buckinghamshire, Oxfordshire, and Berkshire West Integrated Care System (BOBICS) to evaluate A&E attendance.Results In the Modality AWC programme, 40 patients achieved an average HbA1c reduction of 9.9mmol/L, weight loss of 6.2kg, a decrease in alanine aminotransferase (ALT) of 10.3U/L, and a total cholesterol reduction of 0.15mg/dL. Notably, 50% of patients with slightly increased cholesterol experienced reduced triglycerides, indicating improved metabolic health. Additionally, five patients discontinued diabetes medication during the programme. In the Modality Wokingham DRP, 179 patients achieved an average HbA1c decrease of 5.5mmol/mol over 12 months, along with improvements in weight and lipid profiles, and 90% of hypoglycaemic medications were discontinued. Moreover, DRP participants had a 37.7% lower A&E attendance rate than the broader Berkshire West area, equating to 127 fewer visits per 1,000 patients.Conclusions Both DRP programmes show significant potential for improving T2DM management, supporting weight loss, reducing medication dependence and reducing A&E attendance. These interventions offer a promising approach to sustainable diabetes care. Further research is needed to explore long-term outcomes, adherence, and scalability of these programmes across different populations.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.004
metaresearch head score (Gemma)0.007
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Non-randomized trial · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.013
Threshold uncertainty score0.027

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0040.007
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0020.004
Bibliometrics0.0010.001
Science and technology studies0.0010.000
Scholarly communication0.0010.000
Open science0.0010.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0050.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.046
GPT teacher head0.337
Teacher spread0.290 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNon-randomized trial
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

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Citations0
Published2025
Admission routes1
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