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Record W4415715543 · doi:10.26538/tjnpr/v9i10.61

Toxic Beauty: Evaluating the Toxicological Risks of Heavy Metals in Facial Cosmetics and Implications for Public Health in Calabar, Nigeria

2025· article· en· W4415715543 on OpenAlexaboutno aff
Udiba Udiba, Edward Odey Emuru, Michael O. Odey, A.O. Ekwu, Amah Etim, M. Samuel, Keke Sergio, E. R. Akpan

Bibliographic record

VenueTropical Journal of Natural Product Research · 2025
Typearticle
Languageen
FieldMedicine
TopicContact Dermatitis and Allergies
Canadian institutionsnot available
Fundersnot available
KeywordsCosmeticsCadmiumHazard quotientHealth risk assessmentHealth riskHeavy metalsEye irritation

Abstract

fetched live from OpenAlex

Facial cosmetics beautify, but combined usage may expose users to harmful heavy metals. This study evaluates that toxic risk. A survey involving 300 female participants was conducted to identify the most commonly used cosmetic brands—Brands A, B, C, and D. A total of 576 cosmetic samples, including foundations, face powders, lipsticks, and eye pencils, were purchased bimonthly over six months. Samples were prepared through acid digestion and analyzed for metal content using atomic absorption spectrophotometry. Health risk assessment was conducted using systemic exposure dosage (SED), margin of safety (MoS), hazard quotient (HQ), hazard index (HI), and lifetime cancer risk (LCR) models. Metals concentrations (mg/kg) across all brands were in the following ranges: lead (0.066-0.789), cadmium (0.093-0.787), chromium (0.049-0.543), cobalt (0.048-0.902), nickel (0.033-0.704), and iron (0.021-0.641). Metal concentrations varied significantly across brands and product types (ANOVA, p≤0.05). Nickel and cadmium levels in most products exceeded WHO and Health Canada limits. The SED values revealed that Co, Cd, and Pb posed the highest risks, particularly in Brand A and Brand C products. MoS calculations indicated that Cd and Co posed significant safety concerns. HQ values confirmed that Cd and Co exceeded the non-carcinogenic risk threshold. The HI values were above unity, suggesting cumulative health risks. LCR values for Cd, Ni, and Cr were above the acceptable risk range, indicating potential cancer risks. The study concludes that prolonged use of studied cosmetics poses both carcinogenic and non-carcinogenic risks. Routine screening of cosmetic products to ensure compliance with safety standards is strongly recommended.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.011
Threshold uncertainty score0.021

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.001
Science and technology studies0.0010.000
Scholarly communication0.0010.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.350
GPT teacher head0.534
Teacher spread0.183 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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