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Record W4415756440 · doi:10.1038/s41598-026-58421-1

Automated eDNA and eRNA Profiling for Biodiversity Monitoring in Marine and Freshwater Ecosystems

2025· preprint· en· W4415756440 on OpenAlexaffabout
Robert G. Beiko, Jennifer Tolman, Soma Sardar Barawi, Mohamed Fares, T. M. Knox, Connor Mackie, Iain Grundke, Nicholas W. Jeffery, Ryan R. E. Stanley

Bibliographic record

VenueScientific Reports · 2025
Typepreprint
Languageen
FieldEnvironmental Science
TopicEnvironmental DNA in Biodiversity Studies
Canadian institutionsBedford Institute of OceanographyDalhousie University
Fundersnot available
KeywordsEnvironmental DNAMetagenomicsBiodiversitySampling (signal processing)Brackish waterRange (aeronautics)Marine ecosystemSalinityBenthic zone

Abstract

fetched live from OpenAlex

Abstract Automated sampling enables the collection and analysis of eDNA from regions that are limited by site access, sampling times, and operator safety. eDNA sampling devices must be rigorously tested against existing technologies to demonstrate fitness across different operational settings and sample quality. The Dartmouth Ocean Technologies, Inc. (DOT) automated eDNA sampler preserves samples and can be deployed at a range of temperatures and depths. The DOT sampler has previously been tested in marine environments for up to three months, with validation against manual protocols. In this study we tested the DOT sampler in four water bodies in Nova Scotia, Canada, with an expanded set of genetic analyses. We successfully profiled prokaryotes, eukaryotes, and fish using the 16S, 18S, and 12S ribosomal RNA genes respectively, in a brackish pond, a freshwater lake, and two marine harbours. eDNA samples collected by the DOT sampler were statistically concordant with manual Niskin-bottle samples in a range of aqueous habitats. We detected taxonomic groups consistent with the salinity level of each sampled habitat, including invasive species such as smallmouth bass and chain pickerel in the freshwater lake. One marine harbour was sampled at pre-defined time intervals in the days following a significant rainfall event during which site access was limited. We detected ten times as many probable fecal-associated bacteria by proportion at this site relative to the other marine harbour. Onboard preservation of samples in RNAlater allowed the identification of groups with different levels of metabolic activity, and shotgun metagenomic analysis identified key metabolic pathways and a small number of sequences with homology to known antimicrobial-resistance genes.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.103
Threshold uncertainty score0.205

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0020.001
Science and technology studies0.0010.000
Scholarly communication0.0010.000
Open science0.0000.001
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.017
GPT teacher head0.232
Teacher spread0.215 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2025
Admission routes2
Has abstractyes

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