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Record W4415788447 · doi:10.1007/s40279-025-02328-w

Incidence of and Risk Factors for Lower Extremity Apophysitis in Children and Adolescents

2025· article· en· W4415788447 on OpenAlexafffund
Niels Wedderkopp, Chinchin Wang, Russell Steele, Jeffrey J. Hébert, Christina Trifonov Rexen, Eva Jespersen, Tina Junge, Ian Shrier

Bibliographic record

VenueSports Medicine · 2025
Typearticle
Languageen
FieldHealth Professions
TopicOccupational Health and Performance
Canadian institutionsJewish General HospitalUniversity of New BrunswickMcGill University
FundersCanadian Institutes of Health ResearchTrygFondenIMK Almene FondNordea-fondenSyddansk UniversitetDansk Kiropraktor ForeningTeam DanmarkRegion Syddanmark
KeywordsIncidence (geometry)Sports medicineDanishEpidemiologyRisk factorMEDLINE

Abstract

fetched live from OpenAlex

INTRODUCTION: Apophysitis is a common musculoskeletal injury in children and adolescents often resulting in pain and deformity such as bony prominences in Osgood-Schlatter, leading to reduced physical function. A concerning consequence of lower extremity (LE) apophysitis is its potential to reduce physical activity. OBJECTIVES: We aimed to describe the incidence of lower extremity apophysitis in children and estimate the association of leisure-time sport (LT-sport) participation and physical education (PE) on apophysitis incidence. METHODS: In a 5.5-year prospective cohort study of primary-school students, parents sent weekly text messages reporting injury occurrences and LT-sport participation data in the participating children. Injury reports triggered subsequent clinical evaluation. RESULTS: We analyzed data from 878 girls and 792 boys and identified 1265 episodes of apophysitis in 1670 children. Sever's, Sinding-Larsen-Johansson's, and Osgood-Schlatter's diseases constituted more than 99% of LE-apophysitis cases. The median time of injury duration was 3-4 weeks, and the range was between 1 and 45 weeks. The incidence was between 3.2 and 7.0 cases of LE apophysitis per 1000 LT-sport participations. Extra physical education did not increase the risk of apophysitis, whereas children who participated in soccer, handball, basketball, and jump gymnastics were at increased risk (risk ratio [RR] = 2.07-2.74). CONCLUSIONS: Lower extremity apophysitis can result in months of pain. This is important as prolonged periods of injury could reduce LT-sport and exercise participation, thereby decreasing health-related physical activity in childhood. Our results suggest early diagnosis and activity modification in children and adolescents with apophysitis may reduce injury duration, but future intervention studies are required before more definitive causal conclusions can be drawn. TRIAL REGISTRATION: Danish Data Protection Agency (J. no. 2008-41-2240) and ClinicalTrials.gov (NCT03510494).

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.011
Threshold uncertainty score0.311

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.018
GPT teacher head0.388
Teacher spread0.370 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations2
Published2025
Admission routes2
Has abstractyes

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