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Record W4415918632 · doi:10.1097/md.0000000000045303

Eagle’s syndrome with stylohyoid chain pseudoarthrosis and thyrohyoid ligament ossification: A case report and literature review

2025· review· en· W4415918632 on OpenAlexaff
Hui Li, Siqing Zhang, Lei Zhang, He Liu, Hai-Ying Zheng

Bibliographic record

VenueMedicine · 2025
Typereview
Languageen
FieldMedicine
TopicOropharyngeal Anatomy and Pathologies
Canadian institutionsUniversity of British Columbia
Fundersnot available
KeywordsPresentation (obstetrics)LigamentOssificationSurgical resectionResection

Abstract

fetched live from OpenAlex

RATIONALE: Eagle's syndrome is caused by anatomical variations or ossification of the stylohyoid chain (SHC) and presents with complex, nonspecific symptoms, often leading to delayed diagnosis. Complete ossification of the SHC is exceptionally rare, and reporting such cases may enhance clinical awareness and improve diagnostic accuracy. PATIENT CONCERNS: A 57-year-old man presented with persistent right mandibular pain lasting over 4 months. The pain intensified with mouth opening, swallowing, or head tilting, and radiated beneath the right earlobe. Conservative treatments including anti-inflammatory medication, nerve block therapy, and acupuncture were ineffective. DIAGNOSES: Physical examination revealed tenderness and swelling under the right earlobe, pain in the right floor of the mouth, and moderate limitation of mouth opening. Multilayer spiral CT with 3-dimensional reconstruction demonstrated complete ossification and thickening of the right SHC, elongation of the left styloid process, and ossification of the left lateral thyrohyoid ligament, confirming Eagle's syndrome. INTERVENTIONS: Extraoral surgical resection was performed, including excision of the ossified stylohyoid ligament, the entire styloid process, and partial hyoid bone resection. OUTCOMES: The patient achieved complete pain relief postoperatively. During a long-term follow-up of nearly 5 years, no recurrence was observed. LESSONS: This case illustrates an uncommon presentation of Eagle's syndrome with complete SHC ossification and thyrohyoid ligament involvement. Multilayer spiral CT with 3-dimensional reconstruction provides critical diagnostic and surgical planning value. Surgical resection remains the most effective treatment and should be individualized according to the patient's anatomical features and symptoms.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.002
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Case report · Consensus signal: Case report
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.006
Threshold uncertainty score0.009

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.002
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0060.005
Science and technology studies0.0010.001
Scholarly communication0.0020.003
Open science0.0010.001
Research integrity0.0030.001
Insufficient payload (model declined to judge)0.0030.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.028
GPT teacher head0.338
Teacher spread0.310 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designCase report
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2025
Admission routes1
Has abstractyes

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