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Record W4415948474 · doi:10.1136/bmjopen-2025-105391

Concussions and risk of a subsequent traffic crash: retrospective cohort analysis in Ontario, Canada

2025· article· en· W4415948474 on OpenAlexafffundabout
Donald A. Redelmeier, Vidhi Bhatt, Robert Tibshirani, Samantha S. M. Drover

Bibliographic record

VenueBMJ Open · 2025
Typearticle
Languageen
FieldMedicine
TopicTraumatic Brain Injury Research
Canadian institutionsHealth Sciences CentreSunnybrook HospitalUniversity of TorontoInstitute for Clinical Evaluative SciencesSunnybrook Health Science Centre
FundersCanadian Institutes of Health ResearchCanada Research ChairsPhysicians' Services Incorporated Foundation
KeywordsRetrospective cohort studyConcussionOccupational safety and healthInjury preventionPoison controlSuicide preventionHuman factors and ergonomicsEpidemiologyCohort study

Abstract

fetched live from OpenAlex

BACKGROUND: Concussion is an acute injury that may contribute to short-term limitations and potential long-term risks. OBJECTIVE: To test whether a past concussion is associated with the risk of a subsequent serious motor vehicle crash. DESIGN: Population-based longitudinal cohort analysis. SETTING: Ontario, Canada, from 1 April 2002 to 31 March 2022 (178 emergency departments). PATIENTS: Adults diagnosed with a concussion (cases) or an acute ankle sprain (controls), excluding individuals with a disqualifying illness (blindness, dementia, delirium), severe cases resulting in hospitalisation or those who died within 90 days. PRIMARY MEASURE: Subsequent motor vehicle crash requiring emergency medical care. RESULTS: We identified 3 037 028 patients, including 425 158 with a concussion and 2 611 870 with an ankle sprain. A total of 200 603 patients were injured in a subsequent motor vehicle crash over a median follow-up of 10 years, equal to an absolute risk of 1 in 15 patients (6.64 per 1000 patient-years). Patients with a concussion had a 49% higher motor vehicle crash risk compared with those with ankle sprain (adjusted relative risk=1.49, 95% CI 1.47 to 1.50, p<0.001). The increased risk was particularly high in the early weeks after a concussion, remained independent of other observed risk factors, applied to diverse clinical groups and was further accentuated after repeated concussions. The risk extended across a spectrum of crash severity, was accentuated for single-vehicle events, replicated in analyses with artificial intelligence methods adjusting for confounding and remained distinct from the risks of other unrelated medical emergencies. CONCLUSIONS: This study suggests a significant increased risk of a motor vehicle crash after a concussion that may justify a safety warning from clinicians.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.002
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.016
Threshold uncertainty score0.118

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.002
Meta-epidemiology (narrow)0.0000.001
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0010.004
Science and technology studies0.0020.001
Scholarly communication0.0010.000
Open science0.0010.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.059
GPT teacher head0.389
Teacher spread0.329 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2025
Admission routes3
Has abstractyes

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